Smaller enzyme may make process simpler and more exact.
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References
Zetsche, B. et al. Cell http://dx.doi.org/10.1016/j.cell.2015.09.038 (2015).
Ran, F. A. et al. Nature 520, 186-191 (2015).
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Ledford, H. Alternative CRISPR system could improve genome editing. Nature 526, 17 (2015). https://doi.org/10.1038/nature.2015.18432
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DOI: https://doi.org/10.1038/nature.2015.18432