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Gene Orders in Genomes of Alpha-Proteobacteria: Similarity and Evolution

  • Genetics of Microorganisms
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Abstract

The gene orders in the genomes of nine alpha-proteobacteria were compared using quantitative indices S (the relative number of common pairs of adjacent genes) and L (the mean difference between intergenic distances). A sample of 200 homologous genes, occurring in all 11 strains, was studied. In all of the genomes examined, 20 conserved, “uninterrupted” regions, including in total 63 out of 200 genes, were found. The rate of evolutionary change in the gene order widely varied in different evolutionary lineages. The highest rate (40 to 60 genome rearrangements per 100 Myr) was characteristic of the intercellular parasite Wolbachia (Rickettsiales). Computer simulation has showed that the S to L ratio observed in the sample testified that the probability of large genome rearrangements was somewhat lower than that of small ones.

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Authors and Affiliations

  1. Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, 119991, Russia

    I. A. Zakharov

  2. Paleontological Institute, Russian Academy of Sciences, Moscow, 117647, Russia

    A. V. Markov

Authors
  1. I. A. Zakharov
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  2. A. V. Markov
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Translated from Genetika, Vol. 41, No. 12, 2005, pp. 1624–1633.

Original Russian Text Copyright © 2005 by Zakharov, Markov.

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Zakharov, I.A., Markov, A.V. Gene Orders in Genomes of Alpha-Proteobacteria: Similarity and Evolution. Russ J Genet 41, 1343–1351 (2005). https://doi.org/10.1007/s11177-006-0005-8

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  • DOI: https://doi.org/10.1007/s11177-006-0005-8

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