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Social cognition and idiopathic isolated cervical dystonia

  • Neurology and Preclinical Neurological Studies - Original Article
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Abstract

For a long time, cervical dystonia (CD) has been characterised only by disturbances in motor functioning. Despite accumulating evidence for symptomatology in various non-motor domains, to date no study has investigated social cognition in CD. The aim of this study was to compare performance of CD patients and healthy controls in neurocognitive and socio-cognitive domain. Twenty-five non-depressed patients with CD and 26 healthy controls underwent neuropsychological testing. This involved assessment of cognitive status (general intellect, verbal memory, and executive function), and socio-cognitive functions using a Theory of mind task and self-report on empathy and emotion regulation. In comparison to controls, CD patients displayed significantly decreased cognitive abilities, particularly in executive function and verbal memory tasks. Difficulties in inferring mental states on both cognitive and affective levels were also observed. The largest discrepancies were detected in understanding intentionality in others. Poorer performance in cognitive and socio-cognitive tasks was unrelated to severity of the disease. This is the first evidence of compromised socio-cognitive functions in CD patients, highlighting this domain as another facet of non-motor symptoms of this disease. Future studies should advance our understanding of the extent, nature, and time course of these deficits in other aspects of social cognition in this patient population.

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Authors and Affiliations

  1. CEITEC - Central European Institute of Technology, Masaryk University, Kamenice 753/5, 62500, Brno, Czech Republic

    Kristína Czekóová, Petra Zemánková, Daniel J. Shaw & Martin Bareš

  2. First Department of Neurology, Faculty of Medicine, Masaryk University and St. Anne’s Teaching Hospital, Brno, Czech Republic

    Petra Zemánková & Martin Bareš

  3. Department of Neurology, Medical School, University of Minnesota, Minneapolis, USA

    Martin Bareš

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  1. Kristína Czekóová
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  2. Petra Zemánková
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  3. Daniel J. Shaw
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  4. Martin Bareš
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Correspondence to Kristína Czekóová.

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This research was financially supported by the Ministry of Education, Youth and Sports of the Czech Republic under the Project CEITEC 2020 (LQ1601).

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The authors declare that they have no competing interests.

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Czekóová, K., Zemánková, P., Shaw, D.J. et al. Social cognition and idiopathic isolated cervical dystonia. J Neural Transm 124, 1097–1104 (2017). https://doi.org/10.1007/s00702-017-1725-8

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  • DOI: https://doi.org/10.1007/s00702-017-1725-8

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