Skip to main content
Log in

Analysis of Mitochondrial DNA variation in the population of oroks

  • Human Genetics
  • Published:
Russian Journal of Genetics Aims and scope Submit manuscript

Abstract

Mitochondrial DNA (mtDNA) variation was studied in population of Oroks (N = 61), the indigenous inhabitants of Eastern Siberia. Most of the mtDNA types examined fell into five haplogroups (C, D, G, M10, and Y) typical of Eastern Eurasian populations. For three haplogroups (D, C, and M10), the founder effect was established. In one individual, a unique lineage belonging to haplogroup HV and typical of Caucasoids was detected.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

REFERENCES

  1. Wallace, D.C., Brown, M.D., and Lott, M.T., Mitochondrial DNA Variation in Human Evolution and Disease, Gene, 1999, vol. 238, pp. 211–230.

    Article  CAS  PubMed  Google Scholar 

  2. Macaulay, V., Richards, M., Hickey, E., et al., The Emerging Tree of West Eurasian mtDNA: A Synthesis of Control-Region Sequences and RFLPs, Am. J. Hum. Genet., 1999, vol. 58, pp. 1309–1322.

    Google Scholar 

  3. Kivisild, T., Tok, H.-V., Parik, J., et al., The Emerging Limbs and Twigs of the East Asian mtDNA Tree, Mol. Biol. Evol., 2002, vol. 19, no. 10, pp. 1737–1751.

    Google Scholar 

  4. Richards, M., Macaulay, V., Hickey, E., et al., Tracing European Founder Lineages in the Near Eastern mtDNA Pool, Am. J. Hum. Genet., 2000, vol. 67, pp. 1251–1276.

    Google Scholar 

  5. Richards, M., Macaulay, V., and Bandelt, H.J., Phylogeography of Mitochondrial DNA in Western Europe, Ann. Hum. Genet., 1998, vol. 62, pp. 241–260.

    Google Scholar 

  6. Kivisild, T., Bamshad, M., Kaldma, K., et al., Deep Common Ancestry of Indian and Western-Eurasian mtDNA Lineages, Curr. Biol., 1999, vol. 9, pp. 1331–1334.

    Google Scholar 

  7. Finilla, S., Lehtonen, M., and Majamaa, K., Phylogenetic Network for European mtDNA, Am. J. Hum. Genet., 2001, vol. 68, pp. 1475–1484.

    Google Scholar 

  8. Torroni, A., Schurr, T., Cabell, M., et al., Asian Affinities and Continental Radiation of the Four Founding Native American mtDNAs, Am. J. Hum. Genet., 1993, vol. 53, pp. 563–590.

    Google Scholar 

  9. Torroni, A., Sukernik, R.I., Schurr, T., et al., mtDNA Variation of Aboriginal Siberians Reveals Distinct Affinities with Native Americans, Am. J. Hum. Genet., 1993, vol. 53, pp. 591–608.

    Google Scholar 

  10. Cavalli-Sforza, L.L., Menozzi, P., and Piazza, A., The History and Geography of Human Genes, Princeton: Princeton Univ. Press, 1994, p. 274.

    Google Scholar 

  11. Schurr, T., Sukernik, R., Starikovskaya, Y., et al., Mitochondrial DNA Variation in Koryaks and Itel’men: Population Replacement in the Okhotsk Sea-Bering Sea Region during the Neolithic, Am. J. Phys. Anthropol., 1999, vol. 108, pp. 1–39.

    Google Scholar 

  12. Starikovskaya, Y., Sukernik, R., Schurr, T., et al., MtDNA Diversity in Chukchi and Siberian Eskimos: Implications for the Genetic History of Ancient Beringia and the Peopling of the New World, Am. J. Hum. Genet., 1998, vol. 63, pp. 1473–1491.

    Google Scholar 

  13. Derenko, M., Malyarchuk, B., Dambueva, I., et al., Mitochondrial DNA Variation in Two South Siberian Aboriginal Populations: Implications for the Genetic History of North Asia, Hum. Biol., 2000, vol. 72, pp. 945–973.

    Google Scholar 

  14. Sukernik, R.I., Schurr, T.G., Starikovskaya, E.V., and Wallace, D.C., Mitochondrial DNA Variation in Native Siberians with Special Reference to the Evolutionary History of American Indians: I. Studies on Restriction Polymorphism, Rus. J. Genet., 1996, vol. 32, no. 3, pp. 376–382.

    Google Scholar 

  15. Golubenko, M.V., Puzyrev, V.P., Salukov, V.B., et al., Distribution of “Mongoloid” Haplogroups of Mitochondrial DNA among Indigenous Population of the Tuva Republic, Rus. J. Genet., 2001, vol. 37, no. 6, pp. 683–691.

    Google Scholar 

  16. Derenko, M.V., Denisova, G.A., Malyarchuk, B.A., et al., The Structure of the Gene Pools of the Ethnic Populations of Altai-Sayan Region Based on Mitochondrial DNA Polymorphism Data, Rus. J. Genet., 2001, vol. 37, no. 10, pp. 1177–1184.

    Google Scholar 

  17. Fedorova, S.A., Bermisheva, M.A., Villems, R., et al., Analysis of Mitochondrial DNA Lineages in the Orok Population, Mol. Biol. (Moscow), 2003, vol. 37, no. 4, pp. 643–653.

    Google Scholar 

  18. Torroni, A., Schurr, T., Yang, C., et al., Native American Mitochondrial DNA Analysis Indicates that the Amerind and the Nadene Populations Were Founded by Two Independent Migrations, Genetics, 1992, vol. 130, pp. 153–162.

    Google Scholar 

  19. Smolyak, A.K., Etnicheskie protsessy u narodov Nizhnego Amura i Sakhalina (Ethnic Processes in the Populations of Lower Amur Region and Sakhalin), Moscow: Nauka, 1975.

    Google Scholar 

  20. Bruk, S.I., Naselenie mira. Etnodemograficheskii spravochnik (Global Population: An Ethnodemographic Handbook), Moscow: Nauka. 1986

    Google Scholar 

  21. Petrova, T., Yazyk orokov (ul’ta) (Language of Oroks (Ul’ta)), Moscow, 1967.

  22. Anderson, S., Bankier, A.T., Barrell, B.G., et al., Sequence and Organization of the Human Mitochondrial Genome, Nature, 1981, vol. 290, pp. 457–465.

    CAS  PubMed  Google Scholar 

  23. Yao, Y.-G., Kong, Q.-P., Bandelt, H.-J., et al., Phylogeographic Differentiation of Mitochondrial DNA in Han Chinese, Am. J. Hum. Genet., 2002, vol. 70, pp. 635–651.

    Google Scholar 

  24. Comas, D., Calafell, F., Mateu, E., et al., Trading Genes along the Silk Road: mtDNA Sequences and the Origin of Central Asian Populations, Am. J. Hum. Genet., 1998, vol. 63, pp. 1824–1838.

    Google Scholar 

  25. Kolman, C., Sambuughin, N., and Bermingham, E., Mitochondrial DNA Analysis of Mongolian Population and Implications for the Origin of New World Founders, Genetics, 1996, vol. 142, pp. 1321–1334.

    Google Scholar 

  26. Yao, Y.-G., Lu, X.-M., Luo, H.-R., et al., Gene Admixture in the Silk Road Region of China-Evidence from mtDNA and Melanocortin-1 Receptor Polymorphism, Genes Genet. Syst., 2000, vol. 75, pp. 173–178.

    Google Scholar 

  27. Forster, P., Harding, R., Torroni, A., et al., Origin and Evolution of Native American mtDNA Variation: A Reappraisal, Am. J. Hum. Genet., 1996, vol. 59, pp. 935–945.

    Google Scholar 

  28. Lee, S., Shin, S., Kim, K., et al., Sequence Variation of Mitochondrial DNA Control Region in Koreans, Forens. Sci. Int., 1997, vol. 87, pp. 99–116.

    Google Scholar 

  29. Horai, S., Murayama, K., Hayasaka, K., et al., MtDNA Polymorphism in East Asian Populations, with Special Reference to the Peopling of Japan, Am. J. Hum. Genet., 1996, vol. 59, pp. 579–590.

    Google Scholar 

  30. Metspalu, E., Kivisild, T., Kaldma, K., et al., The Trans-Caucasus and the Expansion of the Caucasoid-Specific Human Mitochondrial DNA, Genomic Diversity, New York: Kluwer Academic/Plenum, 1999, pp. 121–134.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Translated from Genetika, Vol. 41, No. 1, 2005, pp. 78–84.

Original Russian Text Copyright © 2005 by Bermisheva, Kutuev, Spitsyn, Villems, Batyrova, Korshunova, Khusnutdinova.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bermisheva, M.A., Kutuev, I.A., Spitsyn, V.A. et al. Analysis of Mitochondrial DNA variation in the population of oroks. Russ J Genet 41, 66–71 (2005). https://doi.org/10.1007/PL00022112

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/PL00022112

Keywords

Navigation