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Long-term stress-induced analgesia blocked by scopolamine

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Abstract

An ‘opioid’ form of analgesia (‘long-term analgesia’) was completely blocked by scopolamine. This effect of a muscarinic antagonist suggests that muscarinic cholinergic processes may play an important role in this analgesia and in other types of endogenous pain control.

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Authors and Affiliations

  1. Department of Psychology, University of Colorado, Campus Box 345, 80309, Boulder, CO, USA

    A. John MacLennan, Robert C. Drugan & Steven F. Maier

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  1. A. John MacLennan
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  2. Robert C. Drugan
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  3. Steven F. Maier
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MacLennan, A.J., Drugan, R.C. & Maier, S.F. Long-term stress-induced analgesia blocked by scopolamine. Psychopharmacology 80, 267–268 (1983). https://doi.org/10.1007/BF00436167

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  • DOI: https://doi.org/10.1007/BF00436167

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