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The Use of Electrospinning Technique on Osteochondral Tissue Engineering

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Book cover Osteochondral Tissue Engineering

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1058))

Abstract

Electrospinning, an electrostatic fiber fabrication technique, has attracted significant interest in recent years due to its versatility and ability to produce highly tunable nanofibrous meshes. These nanofibrous meshes have been investigated as promising tissue engineering scaffolds since they mimic the scale and morphology of the native extracellular matrix. The sub-micron diameter of fibers produced by this process presents various advantages like the high surface area to volume ratio, tunable porosity, and the ability to manipulate the nanofiber composition in order to get desired properties and functionality. Electrospun fibers can be oriented or arranged randomly, giving control over both mechanical properties and the biological response to the fibrous scaffold. Moreover, bioactive molecules can be integrated with the electrospun nanofibrous scaffolds in order to improve the cellular response. This chapter presents an overview of the developments on electrospun polymer nanofibers including processing, structure, and their applications in the field of osteochondral tissue engineering.

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Authors and Affiliations

  1. 3B’s Research Group—Biomaterials, Biodegradable and Biomimetics, Avepark—Parque de Ciência e Tecnologia, Zona Industrial da Gandra, Barco/Guimarães, Portugal

    Marta R. Casanova, Rui L. Reis, Albino Martins & Nuno M. Neves

  2. ICVS/3B’s—PT Government Associate Laboratory, Braga/Guimarães, Portugal

    Marta R. Casanova, Rui L. Reis, Albino Martins & Nuno M. Neves

Authors
  1. Marta R. Casanova
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  2. Rui L. Reis
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  3. Albino Martins
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  4. Nuno M. Neves
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Correspondence to Nuno M. Neves .

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Editors and Affiliations

  1. 3B’s Research Group – Biomaterials, Biodegradables and Biomimetics University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Barco, Guimarães, Portugal

    J. Miguel Oliveira

  2. 3B’s Research Group – Biomaterials, Biodegradables and Biomimetics University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Barco, Guimarães, Portugal

    Sandra Pina

  3. 3B’s Research Group – Biomaterials, Biodegradables and Biomimetics University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Barco, Guimarães, Portugal

    Rui L. Reis

  4. Polymeric Nanomaterials and Biomaterials Department, Institute of Polymer Science and Technology, Spanish Council for Scientific Research (CSIC), Madrid, Spain

    Julio San Roman

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Casanova, M.R., Reis, R.L., Martins, A., Neves, N.M. (2018). The Use of Electrospinning Technique on Osteochondral Tissue Engineering. In: Oliveira, J., Pina, S., Reis, R., San Roman, J. (eds) Osteochondral Tissue Engineering. Advances in Experimental Medicine and Biology, vol 1058. Springer, Cham. https://doi.org/10.1007/978-3-319-76711-6_11

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