Issue 8, 2006
From the journal:

Analyst

Layer guided-acoustic plate mode biosensors for monitoring MHC–peptide interactions†

S. M. Stanley,a   I. A. Dodi,a   C. R. Evans,a   S. J. Paston,c   R. C. Rees,a   C. J. Percival,b   G. McHalea  and  M. I. Newton*a  

* Corresponding authors

a School of Biomedical & Natural Sciences, Nottingham Trent University, Clifton Lane, Nottingham, UK
E-mail: michael.newton@ntu.ac.uk
Fax: +44 115 8483365
Tel: +44 115 8486636

b School of Earth, Atmospheric and Environmental Sciences, , Sackville Building, The University of Manchester, Sackville Street, P.O. Box 88, Manchester, UK

c The Anthony Nolan Research Institute, The Anthony Nolan Trust, Royal Free Hospital, Pond Street, London, UK

Abstract

The transduction signals from the immobilisation of a class I heavy chain, HLA-A2, on a layer guided acoustic plate mode device, followed by binding of β2-microglobulin and subsequent selective binding of a target peptide are reported.

Graphical abstract: Layer guided-acoustic plate mode biosensors for monitoring MHC–peptide interactions

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Article information

DOI
https://doi.org/10.1039/B604812A
Article type
Communication
Submitted
03 Apr 2006
Accepted
16 Jun 2006
First published
28 Jun 2006

Analyst, 2006,131, 892-894

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Layer guided-acoustic plate mode biosensors for monitoring MHC–peptide interactions

S. M. Stanley, I. A. Dodi, C. R. Evans, S. J. Paston, R. C. Rees, C. J. Percival, G. McHale and M. I. Newton, Analyst, 2006, 131, 892 DOI: 10.1039/B604812A

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