Abstract
It is a general observation that children with hypothyroidism have delayed sexual maturation and delayed puberty. However, longstanding untreated hypothyroidism could be associated with isosexual precocious puberty. Here we report a nine year old girl with longstanding untreated hypothyroidism presenting with precocious puberty and bilateral multicystic ovaries, which promptly responded to thyroid hormone replacement.
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Indumathi, C.K., Bantwal, G. & Patil, M. Primary hypothyroidism with precocious puberty and bilateral cystic ovaries. Indian J Pediatr 74, 781–783 (2007). https://doi.org/10.1007/s12098-007-0140-9
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DOI: https://doi.org/10.1007/s12098-007-0140-9