Modern Advances in Pharmaceutical Research Vol. 3

Authors

Dr. Pramod Kumar Sharma, (Editor)

Associate Professor, Department of Pharmacology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.

Ivliane Nozadze

Laboratory of Pain and Analgesia, Beritashvili Center for Experimental Biomedicine, 0160 Tbilisi, Georgia.

Merab G. Tsagareli

Laboratory of Pain and Analgesia, Beritashvili Center for Experimental Biomedicine, 0160 Tbilisi, Georgia.

Lucy B. John-Africa

Department of Pharmacology and Toxicology, National Institute for Pharmaceutical Research and Development, Idu Abuja, Nigeria.

Mercy Aboh

Department of Microbiology, Virology and Biotechnology National Institute for Pharmaceutical Research and Development, Idu Abuja, Nigeria.

V. D. Ravichandra

Department of Pharmacognosy, East West College of Pharmacy, Bangalore-91, India.

Padmaa M. Paarakh

Department of Pharmacognosy, The Oxford College of Pharmacy, Bangalore-68, India.

Panchumarthy Ravisankar

Department of Pharmaceutical Analysis, Vignan Pharmacy College, Vadlamudi, Guntur District – 522 213, Andhra Pradesh, India.

Rafik Karaman

Department of Pharmaceutical Sciences, Faculty of Pharmacy, Al-Quds University, Jerusalem, Palestine.

Salma Jumaa

Department of Pharmaceutical Sciences, Faculty of Pharmacy, Al-Quds University, Jerusalem, Palestine.

Gennaro Mecca

Exo Research Organization, Potenza, Italy.

Teet Seene

Institute of Sport Sciences and Physiotherapy, University of Tartu, Ravila 14a, 50411 Tartu, Estonia.

Priit Kaasik

Institute of Sport Sciences and Physiotherapy, University of Tartu, Ravila 14a, 50411 Tartu, Estonia.

Enn Seppet

Institute of General and Molecular Pathology, University of Tartu, Ravila 19, 50411 Tartu, Estonia.

J. N. Kasolo

Department of Physiology, School of Biomedical Sciences, College of Health Sciences, Makererere University, P.O.Box 7072, Kampala, Uganda.

G. S. Bimenya

Department of Pathology, School of Biomedical Sciences, College of Health Sciences, Makererere University, Kampala, Uganda.

L. Ojok

Department of Pathology, Faculty of Veterinary Medicine, Makererere University, Kampala, Uganda.

W. Ogwal-Okeng

Department of Pharmacology and Therapeutics, School of Biomedical Sciences, College of Health Sciences, Makererere University, Kampala, Uganda.

Michael K. McMullen

Life Force Research, Sweden.

Julie M. Whitehouse

Department of Life Sciences, Faculty of Science and Technology, University of Westminster, London W1B 2HW, UK.

Anthony Towell

Department of Psychology, Faculty of Science and Technology, University of Westminster, London W1B 2HW, UK.

Mayara Tania Pinheiro

Natural Products Biotechnology Laboratory, Department of Biological and Health Sciences, Faculty of Pharmaceutical Sciences, Biotechnology, Federal University of Amapá, Macapá, Amapá, Brazil.

Caroline F. Shafik

Viral and Zoonotic Diseases Research Program, U.S. Naval Medical Research Unit No.3, Cairo 11517, Egypt.

Emad W. Mohareb

Viral and Zoonotic Diseases Research Program, U.S. Naval Medical Research Unit No.3, Cairo 11517, Egypt.

Fouad G. Youssef

Viral and Zoonotic Diseases Research Program, U.S. Naval Medical Research Unit No.3, Cairo 11517, Egypt.

Synopsis

This book covers all areas of pharmaceutical research. The contributions by the authors include Sida corymbosa, haemostasis, flavonoids, striated muscle tissue, endurance capacity, oxidative metabolism, medical plants, botanical and phytochemical characteristics, antidiabetic activity, Ficus hispida, alloxan, blood glucose, analgesia, antinociception, hyperalgesia, sensory neurons, nociception, NSAIDs, prodrug design, allodynia, Moringa oleifera roots, phytochemicals, medicinal plant extracts, herbal medicine, acute toxicity, caffeine, heart rate, blood pressure, direct fluorescence assay, respiratory syncytial virus, respiratory tract infections, hydrochlorothiazide, losartan, olmesartan, telmisartan, valsartan etc. This book contains various materials suitable for students, researchers and academicians in the field of pharmaceutical research.

Chapters

Chapter 1
TRP Channels in Physiological Nociception and Pain

Ivliane Nozadze, Merab G. Tsagareli
Chapter 2
Evaluation of the Haemostatic Activities of Sida corymbosa in Rats

Lucy B. John-Africa, Mercy Aboh
Chapter 3
Thermo-TRP Channels in Pain Sensation: An Overview

Merab G. Tsagareli
Chapter 4
Evaluation of Anti-diabetic Potentials of Methanol Extract of Ficus hispida Linn. Leaves against Alloxan Induced Diabetic Rats

V. D. Ravichandra, Padmaa M. Paarakh
Chapter 5
Novel Simultaneous Separation and Quantitative Determination of Four Sartans in Presence of Hydrochlorothiazide by Isocratic RP-HPLC

Panchumarthy Ravisankar
Chapter 6
Prediction of Bitter Taste Receptor’s Active Site

Rafik Karaman, Salma Jumaa, Gennaro Mecca
Chapter 7
Crosstalk between Mitochondria and Myofibrils in Adult and Aging Striated Muscle Tissue: Effect of Increased Functional Activity

Teet Seene, Priit Kaasik, Enn Seppet
Chapter 8
Phytochemicals and Acute Toxicity of Moringa oleifera Roots in Mice

J. N. Kasolo, G. S. Bimenya, L. Ojok, W. Ogwal-Okeng
Chapter 9
Bitters: Time for a New Paradigm

Michael K. McMullen, Julie M. Whitehouse, Anthony Towell
Chapter 10
Study with Medical Plants of Brazilian Amazon

Mayara Tania Pinheiro
Chapter 11
Reliability of the Direct Fluorescence Assay Compared to the Real-time RT-PCR as Respiratory Syncytial Virus Diagnostic Tool

Caroline F. Shafik, Emad W. Mohareb, Fouad G. Youssef