Japanese Journal of Infectious Diseases
Online ISSN : 1884-2836
Print ISSN : 1344-6304
ISSN-L : 1344-6304
Short Communications
Influenza A Virus Infection in Domestic Ferrets
Yudai KurodaAi OkadaHiroshi ShimodaYasutsugu MiwaAkiko WatamoriHiroho IshidaShin MurakamiAyato TakadaTaisuke HorimotoKen Maeda
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2022 Volume 75 Issue 3 Pages 325-327

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Abstract

Ferrets are animals that are known to be susceptible to influenza A virus (IAV) infection. To evaluate the risk of IAV transmission from diseased ferrets to humans, a survey was performed to detect specific antibodies against the H1, H3, H5, and H7 subtypes of IAV. Using enzyme-linked immunosorbent assay for hemagglutinin proteins, we found a high positive rate for the H1 (24.1%) and H3 (5.2%) subtypes. The results were confirmed by a virus neutralization test for representative antibody-positive serum samples. We also detected hemagglutinin and neuraminidase genes in two ferrets showing acute respiratory disease and whose owner was diagnosed with IAV infection; a human H1N1pdm virus was isolated from one of these ferrets. Our findings suggest that attention should be paid to IAV infection from humans to ferrets and vice versa.

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