In order to construct a scientific and efficient integrated support mechanism model, the management process of aerospace products is proposed based on product life cycle management (PLM). The paper analyzes the current situation of equipment whole system and life-span management current situation, and through the analysis of the comprehensive support work at home and abroad, it constructs a comprehensive support system for the whole life cycle of equipment which is suitable for the characteristics of China’s national conditions, and points out the development direction of comprehensive support technology based on PLM. The results show that the method can improve the support performance and quality of weapon equipment and make it in good condition for a long time.