[1]卢 娜,崔朝初,张淑红,等.胞葬作用影响动脉粥样硬化的分子机制研究进展[J].新乡医学院学报,2021,38(3):207-212.[doi:10.7683/xxyxyxb.2021.03.002]
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胞葬作用影响动脉粥样硬化的分子机制研究进展
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《新乡医学院学报》[ISSN:1004-7239/CN:41-1186/R]

卷:
38
期数:
2021年3
页码:
207-212
栏目:
专题报告
出版日期:
2021-03-05

文章信息/Info

作者:
卢 娜崔朝初张淑红刘 刚王现伟
(新乡医学院基础医学院,河南省医用组织再生重点实验室,河南 新乡 453003)
关键词:
动脉粥样硬化胞葬巨噬细胞
分类号:
R364.3
DOI:
10.7683/xxyxyxb.2021.03.002
文献标志码:
A
摘要:
动脉粥样硬化(AS)斑块增大、坏死核心形成及斑块破裂是心脑血管疾病的主要病理基础。胞葬即吞噬细胞将凋亡、死亡、受损或衰老的细胞吞噬、降解的过程,对维持组织平衡、消除炎症、免疫防御具有重要的作用。胞葬功能缺陷导致的斑块内细胞凋亡及坏死细胞清除障碍是推动AS进展的关键因素。本文就巨噬细胞介导的胞葬在AS发生过程中的分子机制研究进展进行阐述,以期为该疾病的防治提供新的思路。

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更新日期/Last Update: 2021-03-05