目的 考察晒干、阴干、热风干燥（40、50、60、70 ℃）、微波干燥和冷冻干燥5种干燥方法对远志筒及根中主要化学成分的影响。方法 运用HPLC法测定不同干燥方法对远志筒及根中远志𠮿酮Ⅲ、3,6'-二芥子酰基蔗糖、远志酸、远志皂苷元、细叶远志皂苷的组成和含量变化；采用单因素方差分析和TOPSIS法对数据进行综合分析。结果 远志筒和根的干燥方法优选顺序存在差异，远志筒不同干燥方法对有效成分影响的优劣排序为微波干燥 > 60 ℃热风干燥 > 50 ℃热风干燥 > 70 ℃热风干燥 > 冷冻干燥 > 40 ℃热风干燥 > 阴干 > 晒干；远志根中，不同干燥方法的排序为微波干燥 > 60 ℃热风干燥 > 阴干 > 晒干 > 50 ℃热风干燥 > 40 ℃热风干燥 > 70 ℃热风干燥 > 冷冻干燥。结论 结合生产实践，微波干燥和60 ℃热风干燥是远志筒和根较适宜的干燥方法，可为远志不同规格药材产地干燥方式的确定提供依据。

Objective To investigate the effects of different drying methods on composition and content of five active constituents in root bark and root of Polgala tenuifoliaroot. Methods The contents of polygalaxanthone Ⅲ, 3,6'-disinapoyl sucrose, polygalacic acid, senegenin, and tenuifolin in root bark and root from different drying samples were determined by HPLC. Then the data analysis was performed by ANOVA and TOPSIS methods. Results There is a difference in the order of drying methods for bark and root of P. tenuifoliaroot. For P. tenuifoliaroot root bark, the order of different drying methods was microwave drying > 60℃ hot-air drying > 50℃ hot-air drying > 70℃ hot-air drying > freeze-drying > 40℃ hot-air drying > shade drying > sun drying; For P. tenuifolia root, the different drying methods were sorted by microwave drying > 60℃ hot-air drying > shade drying > sun drying > 50℃ hot-air drying > 40℃ hot-air drying > 70℃ hot-air drying > freeze-drying. Conclusion Combined with the production practice, this study suggests that microwave drying and hot-air drying at 60℃ are suitable drying methods for P. tenuifoliaroot bark and root, providing a basis for the determination of drying methods for the origin processing of P. tenuifolia.

公益性行业（中医药）科研专项经费项目（201507002）；国家大学生创新计划（201710716011）；陕西省高校青年杰出人才支持计划项目；咸阳市中青年科技领军人才项目