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HOME > Kosin Med J > Volume 31(2); 2016 > Article
Case Report
Biliary Cystadenoma Causing Esophageal Varices
Sung Ju Kang, Tae Hee Lee, Min Gyu Seok, Hyo Jin Yun, Ye Seul Jang, Jun Hyun Byun
Kosin Medical Journal 2016;31(2):191-196.
DOI: https://doi.org/10.7180/kmj.2016.31.2.191
Published online: January 20, 2016

Department of Internal Medicine, College of Medicine, Konyang University, Daejeon, Korea

Corresponding Author: Tae Hee Lee, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Konyang University College of Medicine, 158, Gwanjeodong-ro, Seo-gu, Daejeon 35365, Korea Tel: +82-42-600-9370 Fax: +82-42-600-9090 E-mail: green740@naver.com
• Received: August 18, 2015   • Accepted: September 21, 2015

Copyright © 2016 Kosin University School of Medicine Proceedings

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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  • Biliary cystadenomas are benign but potentially malignant cystic neoplasm. The preferred treatment is radical resection because it is difficult to differentiate a benign from a malignant biliary cystadenoma. A 40 year-old woman presented with moderate abdominal discomfort. Esophageal varix was found up to mid-esophagus on endoscopy. She has no prior history of liver disease or chronic alcohol ingestion. About 15cm sized biliary cystadenoma was diagnosed by ultrasonography, computed tomography and magnetic resonance imaging. Serum level of bilirubin, alanine aminotransferase, alkaline phosphatase, gamma-glutamyl transpeptidase and tumor marker were elevated. The patient underwent US-guided aspiration. Tumor markers from the aspirated fluid are increased. Left hepatectomy was performed to completely remove the cyst. Histology of the resected specimen confirmed a biliary cystadenoma of the liver with ovary-like stroma. Without prior history of liver disease or chronic alcoholic ingestion, incidental finding of esophageal varix could show an important clue for diagnosis of biliary cystadenoma.
Fig. 1.
Abdomen ultrasonography shows a large cystic mass with septae in liver left lobe.
kmj-31-191f1.jpg
Fig. 2.
Computed tomography shows a large cystic lesion with multiple-enhancing septae (arrow).
kmj-31-191f2.jpg
Fig. 3.
Postoperative picture shows large thick walled cystic lesion in left lobe of liver.
kmj-31-191f3.jpg
Fig. 4.
Cyst histology typical of a mucinous cystadenoma(A) Biliary cyst shows ovary like stroma (H &E stain, x400). (B) Arrow demonstrating ovary like stroma.
kmj-31-191f4.jpg
Fig. 5.
Endoscopy image before operation demonstrating esophageal varix upto midesophagus.(A) Follow up endoscopy after lobectomy shows disappearance of esophageal varix.
kmj-31-191f5.jpg
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