1969 Volume 22 Issue 8 Pages 369-377
Incubation of rifamycin S with washed mycelium of Streptomyces mediterranei gives rifamycin B, rifamycin Y and a new substance named rifamycin L. The structure of the latter has been established as the 4-glycolyl ester of rifamycin SV. The glycolic moieties of rifamycin B and L appear to have the same origin. The biogenetic relationships of these rifamycins are discussed.