With industry and commerce developed, the economic growth of the popularity of the domestic leisure industry, lodging industry business hotel is along with development. Known by most domestic business hotels are located in the metropolitan area, convenient transportation, highly convenience can be important considerations and; addition to business and business to meet the accommodation needs of the guests approached the consumer for various hardware and software equipment diversified novel, and services, such as entertainment, e-commerce, catering and business reception areas, etc., it is a subject worth to explore. This study is mainly through questionnaires, the interviewers conducted in a large number of business hotels in Taichung door surveys, and questionnaires are for business guests and tourists to fill out. After the questionnaires completed, recovered by the interviewers and received a total of 584 valid questionnaires, the effective rate was 73%. The resulting data collected by business travelers demographic changes, the use of t-test, one-way ANOVA, Pearson correlation analysis, to explore business hotel related research between service quality and customer satisfaction in domestic lodging industry. The results of study showed that different ＂demographic variables＂ on the lodging industry business hotel ＂service quality＂ significant difference in the quality of ＂customer satisfaction＂; on the other hand, the lodging industry business hotel ＂service quality＂ on the relationship between customer satisfaction is positively related instructions from the practical implications that it has to create effective consumer customers of more repetitions.