Abstract Background There is lacking of empirical evidence showing how Foreign Brides are adapted to or adopting culture after migration to Taiwan. Aims The objectives of this thesis are therefore to investigate the prevalence of being inadequately adapted to four dimensions of language, dietary habit, lifestyle, and transportation and to identify how and whether socio-demographic features, family resources and support, social support are associated with adaptation to culture. Methods A total of 427 foreign brides from Vietnam were enrolled from the target population with the total of 1116 Vietnam foreign brides were interviewed with closed-structure questionnaire including information on adaptation to culture and their correlates pertaining to family and social resources and support. Forward and backward translation for questionnaire was developed. Cumulative logit model was used to assess the incremental effect of family and social resources and support on adaptation to culture in four dimensions after controlling for socio-demographic features. . Results The prevalence rate of any ill-adapted condition among four dimensions was 6.09% with 1.90% for language, 2.80% for dietary habit, 1.40% for life style, and 3.70% for transportation. It takes approximately three years for adaptation to language, dietary habits, and life styles and six years for adaptation to transportation. After controlling for socio-demographic of foreign, good adaptation was noted for those who spoke Taiwanese, longer duration of residence in Taiwan, number of children, high family support such as all ears to hearing, fear of family atmosphere, language training, tendency of violence, and extension of social relationship, and social support like accessibility to medical care. Conclusions The present empirical study demonstrated that family resource and social support play an important role in adaptation to culture for foreign bridges from Vietnam.