12863_2015_272_MOESM1_ESM.doc (3.86 MB)
Additional file 1: of Coronary risk in relation to genetic variation in MEOX2 and TCF15 in a Flemish population
journal contribution
posted on 2015-10-01, 05:00 authored by Wen-Yi Yang, Thibault Petit, Lutgarde Thijs, Zhen-Yu Zhang, Lotte Jacobs, Azusa Hara, Fang-Fei Wei, Erika Salvi, Lorena Citterio, Simona Delli Carpini, Yu-Mei Gu, Judita Knez, Nicholas Cauwenberghs, Matteo Barcella, Cristina Barlassina, Paolo Manunta, Giulia Coppiello, Xabier Aranguren, Tatiana Kuznetsova, Daniele Cusi, Peter Verhamme, Aernout Luttun, Jan StaessenTable S1. Common tagging SNPs in MEOX2. Table S2. MEOX2 and TCF15 SNPs and allele and genotype frequencies in unrelated founders. Table S3. MEOX2 and TCF15 allele and genotype frequencies in 2027 analysed participants. Table S4. Sex- and age-standardised CHD rates by MEOX2 SNPs. Table S5. Hazard ratios for CHD by MEOX2 SNPs in participants free of CHD at baseline. Table S6. Sex- and age-standardised CHD rates by MEOX2 haplotypes. Table S7. Hazard ratios for CHD by MEOX2 haplotypes reconstructed while accounting for pedigree information. Table S8. Hazard ratios for CHD by MEOX2 haplotypes in participants free of CHD at baseline. Table S9. Baseline characteristics of participants without blood left for genotyping compared with those included in the analyses. Figure S1. Plot of the MEOX2 gene and flanking regions on chromosome 7. Figure S2. Plot of the TCF15 gene and flanking regions on chromosome 20. Figure S3. Interaction between TCF15 rs12624577 and MEOX2 rs4532497. Figure S4. Incidence of coronary endpoints, myocardial infarction and coronary revascularisation in MEOX2 GTCCGC carriers and non-carriers.
