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Additional file 3 of Complete representation of a tapeworm genome reveals chromosomes capped by centromeres, necessitating a dual role in segregation and protection

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posted on 2020-11-10, 04:42 authored by Peter D. Olson, Alan Tracey, Andrew Baillie, Katherine James, Stephen R. Doyle, Sarah K. Buddenborg, Faye H. Rodgers, Nancy Holroyd, Matt Berriman
Additional file 3: Figure S1. Mitochondrial genome. The 13,919 bp Hymenolepis microstoma mitochondrial genome was re-assembled from both short and long-read data, yielding over 1000x coverage. The new assembly resolved the full length of a region involving a tandemly repeated 32 bp motif (cf. GenBank accession AP017665.1). This region is identified as one of three origins of replication-heavy strand (OH-a) by MITOS [61] and an adjacent hairpin-loop region as the origin of replication-light strand (OL). Gene order of ribosomal and protein-coding genes is consistent with the hypothesized ground-plan for the mitogenomes of parasitic flatworms as is the absence of the atp8 gene [89].

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Wellcome Trust Biotechnology and Biological Sciences Research Council

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