NANOSTRUCTURES CONTAINING BIOACTIVE COMPOUNDS EXTRACTED FROM PLANTS
DOI:
https://doi.org/10.5902/2179460X19743Keywords:
Plant extracts. Nanotechnology. Nanoparticles. Liposomes. Nanoemulsions.Abstract
Many natural compounds, extracted from fruits and vegetables, have promising potential for maintaining and promoting health as well as preventing and treating some diseases. In the food industry, the use of plant extracts, as an alternative to chemical or synthetic antioxidants and antimicrobials to combat the foodborne pathogens, inhibiting lipid oxidation and thus extending the shelf life is an increasing trend. However, most of bioactive compounds present in these extracts such as polyphenols, carotenoids, alkaloids, among others, have low water solubility, stability and bioavailability. In this sense, nanotechnology is an innovative approach that has potential applications in nutraceutical research, since it improves these characteristics, besides enhance their absorption, protect them from premature degradation in the body and prolong their circulation time. There are different nanostructured systems that can be used in foods such as liposome, polymeric nanoparticles, lipid solid nanoparticles and nanoemulsions. This work presents a review of the main nanostructured systems used for association of different plant extracts and some technological applications.
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Abbas, S., Karangwa, E., Bashari, M., Hayat, K., Hong, X., Sharif, H. R., Zhang, X. (2015) Fabrication of polymeric nanocapsules from curcumin-loaded nanoemulsion templates by self-assembly. Ultrasonics Sonochemistry 23, 81–92.
Anandharamakrishnan, C. (2014). Techniques for Nanoencapsulation of Food Ingredients, Springer.
Anton, N., Benoit, J. P., Saulnier, P. (2008). Design and production of nanoparticles formulated from nano-emulsion templates—A review. Journal of Controlled Release 128, 185–199.
Arana, L., Salado, C., Vega, S., Aizpurua-Olaizola, O., Arada, I., Suarez, T., Usobiaga, A., Arrondo, J. L. R., Alonso, A., Goni, F. G., Alkorta, I. (2015). Solid lipid nanoparticles for delivery of Calendula officinalis extract. Colloids and Surfaces B: Biointerfaces, 135, 18-26.
Ajazuddin, S. S. (2010). Applications of novel drug delivery system for herbal formulations. Fitoterapia, 81, 680–689.
Batista, C. M., Carvalho, C. M. B., Magalhães, N. S. (2007). Lipossomas e suas aplicações terapêuticas: Estado da arte. Revista Brasileira de Ciências Farmacêuticas, 43(2), 167-179.
Bhargava, K., Conti, D. S., Rocha, S. R. P., Zhang, Y. (2015). Application of an oregano oil nanoemulsion to the control of foodborne bacteria on fresh lettuce. Food Microbiology, 47, 69-73.
Bonifácio, B. V., Silva, P. B., Ramos, M. A. S., Negri, K. M. S., Bauab, T. M., Chorilli, M. (2014). International Journal of Nanomedicine, 9, 1-15.
Dimer, F. A., Friedrich, R. B., Beck, R. C. R., Guterres, S. S., Pohlmann, A. R. (2013). Impactos da Nanotecnologia Na Saúde: Produção De Medicamentos. Quimica Nova, 36(10), 1520-1526.
Duncan, T. V. Applications of nanotechnology in food packaging and food safety: Barrier materials, antimicrobials and sensors. Journal of Colloid and Interface Science 363 (2011) 1–24.
Fernandez, P., Andre, V., Rieger, J., Kuhnle, K. (2004). Nano-emulsion formation by emulsion phase inversion. Colloids and Surfaces A: Physicochem. Eng. Aspects, 251, 53–58.
Ghorani, B., Tucker, N. (2015). Fundamentals of electrospinning as a novel delivery vehicle for bioactive compounds in food nanotechnology. Food Hydrocolloids, 51, 227-240.
Gibis, M., Vogt, E., Weiss, J. (2012). Encapsulation of polyphenolic grape seed extract in polymer-coated liposomes. Food & Function, 3, 246-254.
Gibis, M., Zeeb, B., Weiss, J. (2014). Formation, characterization, and stability of encapsulated hibiscus extract in multilayered liposomes. Food Hydrocolloids, 38, 28-39.
Gortzi, O., Lalas, S., Chinou, I., Tsaknis, J. (2007). Evaluation of the Antimicrobial and Antioxidant Activities of Origanum dictamnus Extracts before and after Encapsulation in Liposomes. Molecules, 12, 932-945.
Gortzi, O., Lalas, S., Chinou, J., Tsaknis, J. (2008). Reevaluation of bioactivity and antioxidant activity of Myrtus communis extract before and after encapsulation in liposomes. European Food Research and Technology, 226, 583-590.
Guan, Y., Wu, J., Zhong, O. (2016). Eugenol improves physical and chemical stabilities of nanoemulsions loaded with β-carotene. Food Chemistry, 194, 787-796.
Kakkar, V., Singh, S., Singla, D., Kaur, I. P. (2011). Exploring solid lipid nanoparticles to enhance the oral bioavailability of curcumin. Molecular nutrition & food research, 55, 495-503.
Kumar, S., Chauhan, N., Gopal, M., Kumar, R. Dilbaghi, N. (2015). Development and evaluation of alginate–chitosan nanocapsules for controlled release of acetamiprid. International Journal of Biological Macromolecules, 81, 631-637.
Kumari, A., Yadav, S. K., Pakade, Y. B., Singh, B., Yadav, S. C. (2010). Development of biodegradable nanoparticles for delivery of quercetin. Colloids and Surfaces B: Biointerfaces, 80, 184-192.
Lu, Q., Li, D. C., Jiang, J. G. (2011). Preparation of a Tea Polyphenol Nanoliposome System and Its Physicochemical Properties. Journal of Agricultural and Food Chemistry, 59, 13004–13011.
Mehnert, W., Mader, K. (2001). Solid lipid nanoparticles Production, characterization and applications. Advanced Drug Delivery Reviews, 47, 165-196.
Mohammadi, A., Jafari, S. M., Esfanjani, A. F., Akhavan, S. (2016). Application of nano-encapsulated olive leaf extract in controlling the oxidative stability of soybean oil Food Chemistry, 190, 513-519.
Mora-Huertas, C. E.; Fessi, H., Elaissari, A. (2013). Polymer-based nanocapsules for drug delivery. International Journal of Pharmaceutics, 385, 113-142.
Neves, M. A., Hashemi, J., Prentice, C. (2015). Development of novel bioactives delivery systems by micro/nanotechnology. Current Opinion in Food Science, 1, 7-12.
Noronha, C. M., Granada, A. F., Carvalho, S. M., Lino, R. C., Maciel, M. V. O. B., Barreto, P. L. M. (2013). Optimization of α-tocopherol loaded nanocapsules by the nanoprecipitation method. Industrial Crops and Products, 50, 896-903.
Nuengchamnong, N., Hermans-Lokkerbol, A., Ingkaninan, K. (2004). Separation and Detection of the Antioxidant Flavonoids, Rutin and Quercetin, Using HPLC Coupled on-line With Colorimetric Detection of Antioxidant Activity. Naresuan University Journal, 12(2): 25-37.
Pardeike, J., Hommoss, A., Müller, R. H. (2009). Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products. International Journal of Pharmaceutics, 366, 170-184.
Patidar, A., Thakur, D. S., Kumar, P., Verma, J. (2010). A Review on Novel Lipid Based Nanocarriers. International Journal of Pharmacy and Pharmaceutical Sciences, 2(4), 30-35.
Perumalla, A. V. S., Hettiarachchy, N. S. (2011). Green tea and grape seed extracts — Potential applications in food safety and quality. Food Research International, 44, 827-839.
Qian, C., Decker, E. A., Xiao, H., McClements, D. J. (2012). Nanoemulsion delivery systems: Influence of carrier oil on β-carotene bioaccessibility. Food Chemistry, 135, 1440-1447.
Quintão, F. J. O., Tavares, R. S. N., Vieira-Filho, S. A., Souza, G. H. B., Santos, O. D. H. (2013). Hydroalcoholic extracts of Vellozia squamata: study of its nanoemulsions for pharmaceutical or cosmetic applications. Revista Brasileira de Farmacognosia, 23(1), 101-107.
Salminen, H., Gömmel, C., Leuenberger, B. H., Weiss, J. (2016). Influence of encapsulated functional lipids on crystal structure and chemical stability in solid lipid nanoparticles: Towards bioactive-based design of delivery systems. Food Chemistry, 190, 928-937.
Schaffazick, S. R., Guterres, S. S., Freitas, L. L., Pohlmann, A. R. (2003). Caracterização e estabilidade físico-química de sistemas poliméricos nanoparticulados para administração de fármacos. Quimica Nova, 26(5), 726-737, 2003.
Schmaltz, C., Santos, J. V., Guterres, S. S. (2005). Nanocápsulas como uma tendência promissora na área cosmética: A imensa potencialidade deste pequeno grande recurso. Infarma, 16, 13-14.
Shin, G. H., Kim, J. T., Park, H. J. (2015). Recent developments in nanoformulations of lipophilic functional foods. Trends in Food Science & Technology, in Press.
Silva, L. M., Hill, L. E., Figueiredo, E., Gomes, C. L. (2014). Delivery of phytochemicals of tropical fruit by-products using poly(DL-lactide-co-glycolide) (PLGA) nanoparticles: Synthesis, characterization, and antimicrobial activity. Food Chemistry, 165, 362-370.
Silva Junior, E., Zanon Junior, G. B., Zanella, I., Raffin, R., Cielo, V., Rossato, J., Bulhões, L. O. S. (2013). Formação de nanoemulsões do tipo óleo em água contendo óleo de semente de romã. Disciplinarum Scientia. Série: Ciências Naturais e Tecnológicas, 14(1), 115-122.
Spigno, G., Donsì, F., Amendola, D., Sessa, M, Ferrari, G., D. Faveri, M. (2013). Nanoencapsulation systems to improve solubility and antioxidant efficiency of a grape marc extract into hazelnut paste. Journal of Food Engineering, 114, 207-214.
Solans, C., Izquierdo, P., Nolla, J., Azemar, N. (2005). Nano-emulsions. Current Opinion in Colloid & Interface Science, 10(3-4), 102-110.
Wang, S., Marcone, M F., Barbut, S., Lim, L. T. (2012). Fortification of dietary biopolymers-based packaging material with bioactive plant extracts. Food Research International, 49, 80-91.
Wang, S., Su, R., Nie, S., Sun, M., Zhang, J., Wu, D., Moustaid-Moussa, N. (2014). Application of nanotechnology in improving bioavailability and bioactivity of diet-derived phytochemicals. Journal of Nutritional Biochemistry, 25, 363-376.
Xie, X., Tao, Q., Zou, Y., Zhang, F., Guo, M., Wang,Y., Wang, H., Zhou, Q., Yu, S. (2011). PLGA Nanoparticles Improve the Oral Bioavailability of Curcumin in Rats: Characterizations and Mechanisms. Journal of Agricultural and Food Chemistry, 59, 9280-9289.
Zorzi, G. K., Carvalho, E. L. S., Poser, G. L., Teixeira, H. F. (2015). On the use of nanotechnology-based strategies for association ofcomplexes matrices from plant extracts. Revista Brasileira de Farmacognosia, in press.
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