Olfactory neuroblastoma, a malignant tumor arising from the olfactory epithelium, is treated combining surgery and radiotherapy. Many reports have also cited the effectiveness of chemotherapy.
We report a case of olfactory neuroblastoma in a 64-year-old-man responding well to chemotherapy. Computer tomography and magnetic resonance imaging showed a large mass in the bilateral nasal cavity, maxillary sinus, and ethmoid sinus with a clinical Kadish staging score of stage B. After 2 cycles of cisplatin and irinotecan chemotherapy and additional radiotherapy of 60 Gy, endoscopic resection achieved a complete pathological response. No recurrence was noted in the 20 months after diagnosis, and he died of pancreatic cancer.