Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2022, 166(3):258-266 | DOI: 10.5507/bp.2021.065

Sudden cardiac death - a known unknown?

Jana Obrovaa, Eliska Sovovab, Eva Kocianovaa, Milos Taborskya
a Department of Internal Medicine I - Cardiology, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacky University Olomouc, Czech Republic
b Department of Exercise Medicine and Cardiovascular Rehabilitation, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacky University Olomouc, Czech Republic

Sudden cardiac death (SCD) is a major medical, economic and social problem. The estimated annual number of SCDs is approximately 4 million cases worldwide. Approximately 50% of SCDs are unexpected first manifestations of cardiac disease. The survival rate after out-of-hospital cardiac arrest is low even in countries with the most advanced health care systems. It all emphasizes the importance of prevention, in which implantable cardioverter-defibrillators play a dominant role. However, our ability to recognize high-risk patients remains insufficient. Moreover, a declining rate of shockable rhythm as the initial recording has been reported in the last decades. Despite numerous SCD studies and undisputed progress, there are still many unanswered questions.

Keywords: sudden cardiac death, mechanism, prevention, risk stratification, implantable cardioverter-defibrillator

Received: July 9, 2021; Revised: October 18, 2021; Accepted: November 5, 2021; Prepublished online: November 15, 2021; Published: September 14, 2022  Show citation

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Obrova, J., Sovova, E., Kocianova, E., & Taborsky, M. (2022). Sudden cardiac death - a known unknown? Biomedical papers166(3), 258-266. doi: 10.5507/bp.2021.065
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