Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2008, 152(1):65-71 | DOI: 10.5507/bp.2008.010

EVALUATION OF THE NEW SOFTWARE PROGRAM DEGIFXL4 IN THE DETERMINATION OF THE GLYCAEMIC INDICES OF FOODSTUFFS

Helena Pribylovaa, Maria Pallayovab, Jarmila Hucikovaa, Jiri Luzaa
a Department of Physiology and 2nd Department of Medicine, Faculty of Medicine and Dentistry, Palacky University, 775 15 Olomouc, Czech Republic
b Department of Physiology and 1st Department of Medicine, Faculty of Medicine, P. J. Šafárik University, Košice, Slovak Republic

Aims: There is no standardized protocol for measuring glycemic index (GI) that takes time-of-day effects into account. The software DegifXL2 and Medtronic-Minimed's CGMS and Solutions, makes the GI calculation at breakfast and dinner time possible. The aim of this study was to assess the enhanced data processing software (DegifXL4) enabling the GI calculation at breakfast, lunch, afternoon snack and dinner times.

Methods: The glucose levels of 20 healthy volunteers were monitored after they consumed either 50 g of glucose or one of ten alternative foodstuffs either for breakfast and dinner or for lunch or snack. Within the 9-day test period, 10 such meals were monitored in 3 replicates for each volunteer. Specifically, CGMS was used to monitor plasma glucose levels at 5-minute intervals for a period of 120 min following the foodstuff ingestion.

Results: Using the enhanced spreadsheed DegifXL 4, a total of 640 profiles were obtained and 491 (77 %) accomplished the criteria for further processing. The percentage of successful tests in each foodstuff varied from 57 to 87 %.

Conclusions: The use of the new software DegifXL4 offers accurate GI estimates for foodstuffs eaten for breakfast, lunch, snacks and dinners in three replicates. In combination with the CGMS Solutions Software is DegifXL4 an enhanced efficient and comfortable way to routinely measure GI values.

Keywords: Nutrition, Glycaemic index, Continuous glucose monitoring, Data processing, DegifXL software

Received: August 8, 2008; Accepted: October 10, 2008; Published: June 1, 2008  Show citation

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Pribylova, H., Pallayova, M., Hucikova, J., & Luza, J. (2008). EVALUATION OF THE NEW SOFTWARE PROGRAM DEGIFXL4 IN THE DETERMINATION OF THE GLYCAEMIC INDICES OF FOODSTUFFS. Biomedical papers, 152(1), 65-71. doi: 10.5507/bp.2008.010
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    References

    1. Chlup R, Jelenová D, Kudlová P, Chlupová K, Bartek J, Zapletalová J, Langová K, Chlupová L: Continuous glucose monitoring a novel approach to the determination of the glycaemic index of foods (DEGIF 1). Exp Clin Endocrinol Diabetes 2006; 114:68- 74. Go to original source... Go to PubMed...
    2. Chlup R, Seckar P, Zapletalova J, Langova K, Kudlova P, Peterson K, Bartek J, Hucikova J. DegifXL a new software program for determination of group-related and person-related glycemic indexes of foods by means of continuous glucose monitoring system CGMS. Acta Diab. Romana 2007; 33(1):351.
    3. Chlup R, Seckar P, Zapletalova J, Langova K, Kudlova P, Chlupova K et al. Automated computation of glycemic index for foodstuff s using continuous glucose monitoring. J Diabetes Sci Technol 2008;2(1) Go to original source... Go to PubMed...
    4. Otto H, Bleyer G, Pennartz M, Sabin G, Schauberger G, Spaethe R: Kohlenhydrataustausch nach biologischen Äquivalenten. In: Otto H, Spaethe R (Ed). Diätetik bei Diabetes mellitus [German: Exchange of Carbohydrates according to biological equivalents. In: Otto H, Spaethe R (Ed). Diet in diabetes mellitus]. Verlag Hans Huber, Bern Stuttgart Wien. 1973:41-50.
    5. Jenkins DJA, Wolever TMS, Taylor RH, Barker H, Fielden H, Baldwin JM, Bowling AC, Newman HC, Jenkins AL, Goff DV: Glycemic index of foods: a physiological basis for carbohydrate exchange. Amer J Clin Nutr 1981; 34:362-366. Go to original source... Go to PubMed...
    6. Ionescu-Tirgoviste C, Popa E, Santu E, Mihalache N, Cheta D, Mincu I: Blood glucose and plasma insulin responses to various carbohydrates in type 2 (non-insulin-dependent) diabetes. Diabetologia 1983; 24:80-84. Go to original source... Go to PubMed...
    7. Bruns W: Behandlung mit Diät. In: Bibergeil H (Ed). Diabetes mellitus. Ein Nachschlagewerk für die diabetologische Praxis [German: Diet treatment. In: Bibergeil H (Ed). Diabetes mellitus. Guidelines for the diabetes practice]. VEB Gustav Fischer Verlag Jena. 1989:254-316.
    8. Chantelau E: The glycaemic index of carbohydrate foods: an update from a diabetologist´s perspective. Aktuel Ernaehr Med 2000; 25:176-185.
    9. Jenkins DJA, Kendall CWC, Augustin LSA, Silvia Franceschi, Hamidi M, Marchie A et al. Glycemic index: overview of implications in health and disease. Am J Clin Nutr 2002; 76:266-273. Go to original source...
    10. Food and Agriculture Organization/World Health Organization. Carbohydrates in human nutrition: report of a Joint FAO/WHO expert consultation. FAO Food and Nutrition Paper 1998; 66:1- 140. Go to PubMed...
    11. Foster-Powell K, Holt SH, Brand-Miller JC. International table of glycemic index and glycemic load values. Amer J Clin Nutr 2002; 76:5-56. Go to original source... Go to PubMed...
    12. Wolever TM, Csima A, Jenkins DJ, Wong GS, Josse RG. The glycemic index: variation between subjects and predictive diff erence. J Am Coll Nutr 1989; 8(3):253-47. Go to original source... Go to PubMed...
    13. Nell T, Venter Ch, Vorster H, Botes I, Steyn F. Intra- and interindividual variation in glucose response to white bread and oral glucose in healthy women. SAJCN 2003; 16:58-64.
    14. Chlup R, Bartek J, Reznickova M, Zapletalova J, Doubravova B, Chlupova L et al. Determination of the glycaemic index of selected foods (white bread and cereal bars) in healthy persons. Biomed Papers 2004; 148:17-25. Go to original source...
    15. Brand-Miller JC, Holt SH, Pawlak DB, McMillan J. Glycemic index and obesity. Am J Clin Nutr 2002; 76(1):281S-5S. Go to original source...
    16. Pi-Sunyer FX. Glycemic index and disease. Am J Clin Nutr 2002; 76(1):290S-8S. Go to original source...
    17. Thomas DE, Brotherhood JR, Brand JC. Carbohydrate feeding before exercise: eff ect of glycemic index. Int J Sports Med 1991; 12(2):180-6. Go to original source... Go to PubMed...
    18. Nakladalova M, Kapoun S. Zdravotni zpusobilost k praci u osob s diabetem. [Czech: Occupational ability in persons with diabetes] Pracovni Lek 2004; 56:13-16.
    19. Granfeldt Y, Wu X, Björck I. Determination of glycaemic index; some methodological aspects related to the analysis of carbohydrate load and characteristics of the previous evening meal. Eur J Clin Nutr 2006; 60:104-112. Go to original source... Go to PubMed...
    20. Wolever TMS, Vorster HH, Bjorck I, Brand-Miller J, Brighenti F, Mann JI et al.. Determination of the glycaemic index of foods: interlaboratory study. Eur J Clin Nutr 2003; 57:475-482. Go to original source... Go to PubMed...
    21. Chlup R, Payne M, Zapletalova J, Komenda S, Doubravova B, Reznickova M et al. Results of selfmonitoring on glucometer systems Advance and Optium in daily routine. Biomed Papers 2005; 149:127-139. Go to original source...
    22. Chlup R., Bartek J, Malá E, Doubravová B, Pukowietz L, Zatloukal P et al. Uživatelská studie o správnosti a přesnosti měření glukometrů Advance, Card a Optium (Useroriented study on accuracy and precision of glucometer systems Advance, Card and Optium). Klin Bioch Metabol 2004; 12:171178.
    23. Chlup R, Jelenová D, Chlupová K, Zapletalová J, Chlupová L, Bartek J: Function and accuracy of glucose sensors beyond their stated expiry date. Diabetes Technology&Therapeutics 2006; 8:495- 504. Go to original source... Go to PubMed...
    24. Jadviscokova T, Fajkusova Z, Pallayova M, Luza J, Kuzmina G. Occurence of adverse events due to continous glucose monitoring. Biomed Papers 2007; 151 (2):263-267. Go to original source...
    25. Fajkusova Z, Jadviscokova T, Pallayova M, Luza J, Kuzmina G. Glycaemic index of selected foodstuff s in healthy persons. Biomed papers 2007; 151(2):257-263. Go to original source...
    26. Peterson K, Chlup R, Kudlova P, Slezakova L, Zapletalova J, Langova K et al. Influence of Oral Antidiabetic Drugs on Hyperglycemic Power of Foods In Persons with Type 2 Diabetes Mellitus (DEGIF4). Diabetes 2007; 56. Go to original source... Go to PubMed...
    27. Chlup R, Kudlova P, Peterson K, Slezakova L, Bartek J, Nakladalova M et al. Glykemicky index potravin u osob s diabetem 1. a 2. typu a u zdravych. Diabetes a obezita 2007; 7(13):78-89.
    28. Chlup R, Kudlova P , Seckar P, Zapletalova J, Bartek J, Chlupova K et al. Glycaemic index of foods in healthy persons vs persons with type 1 diabetes mellitus. Diabetes 2006; 55:A593.
    29. Chlup R, Jelenová D , Kudlová P, Bartek J, Nakládalová M, Sečkař P et al. Konventionelle Bestimmung des glykämischen Indexes verschiedener Nahrungsmittel (Schokolade, Apfelmuss, Reisbrot, Yoghurt) bei pumpenbehandelten Typ-1 Diabetikern. Diabetologie und Stoff wechsel 2006; 1:154 Go to original source...
    30. Chlupová K, Kohnert KD, Heinke P, Augstein P, Chlup R, Salzsieder E. Resultate kontinuierlicher Glukosemessungen (CGMS) unter ambulanten Bedingungen zur Beurteilung der Stoff wechseleinstellung bei T2DM. Diabetologie und Stoff wechsel 2006; 1:94. Go to original source...
    31. Mlčák P, Fialová J, Trnková K, Chlup R. A continous glukose monitoring system (CGMS) A promising approach for improving metabolic control in persons with type 1 diabetes mellitus treated by insulin pumps. Biomed. Papers 2004; 148:33-38. Go to original source...
    32. Chew I, Brand JC, Thorburn AW, Truswell AS. Application of glycemic index to mixed meals. Am J Clin Nutr 1988; 47(1):53-6. Go to original source... Go to PubMed...
    33. Kudlová P, Stanislavová A. Edukace zdravých probandů v souvislosti s určováním glykemického indexu potravin (Czech: Education of healthy volunteers for the determination of glycemic index of foods). 1st ed. In: Čáp J, Žiaková K, Nemčeková M, Holmanová E, ed. Teoria, výskum a vzdelávanie v ošetrovatelstve (Theory, research and education in nursing). Univerzita Komenského Bratislava, Jeseniova Lekárska Fakulta Martin, Ústav ošetrovatelstva, SR, Lékařská fakulta Univerzity Palackého Olomouc, Ústav teorie a praxe ošetřovatelství, ČR, Občianské združenie pre rozvoj zdravotníckeho vzdelávania v Martine. 2005:363-372.

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