Open Access, Peer-reviewed
eISSN 2234-7666
    J Korean Acad Conserv Dent. 2004 Sep;29(5):462-469. Korean.
    Published online Sep 30, 2004.
    https://doi.org/10.5395/JKACD.2004.29.5.462
    Copyright © 2004 Korean Academy of Conservative Dentistry
    Original Article

    Antibiotic susceptibility in mutans streptococci and Streptococcus anginosus isolated from dental plaque

    Joong-Ki Kook,1,3 Sang-Soo Lim,2,3 So Young Yoo,1,3 and Ho-Keel Hwang2,3
      • 1Department of Oral Biochemistry, College of Dentistry, Chosun University, Korea.
      • 2Department of Conservative Dentistry, College of Dentistry, Chosun University, Korea.
      • 3Oral Biology Research Institute, College of Dentistry, Chosun University, Korea.
    • Corresponding author: Ho-Keel Hwang. Department of Conservative Dentistry, and Oral Biology Research Institute, College of Dentistry, Chosun University 375 Seo-suk Dong, Dong-Gu, Gwang-ju, Korea, 501-749. Tel: 82-62-220-3846, Fax: 82-62-232-9064, Email: rootcanal@hanmail.net

    This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

    Abstract

    The aim of this study was to investigate the susceptibility of mutans streptococci (S. mutans and S. sobrinus) and Streptococcus anginosus, for seven antibiotics, penicillin G, amoxicillin, ciprofloxacin, cefuroxime, erythromycin, bacitracin, and vancomycin. The minimum inhibitory concentration (MIC) of seven antibiotics against 3 species (type strains) of mutans streptococci and S. anginosus, 10 strains (wild type) of S. mutans, 7 strains (wild type) of S. sobrinus, and 11 strains (wild type) of S. anginosus, were measured by broth dilution method. All of the type strains of mutans streptococci and S. anginosus had the same susceptibility for penicillin G, amoxicillin, cefuroxime and bacitracin. Type strain of S. anginosus was sensitive in ciprofloxacin, but those of mutans streptococci were not. All of the clinical isolates of mutans streptococci and S. anginosus had the same susceptibility for the seven antibiotics. Our data reveal that mutans streptococci and S. anginosus have similar antibiotic-resistant character. In addition, these results may offer the basic data to verify the antibiotic-resistant mechanism of mutans streptococci and S. anginosus.

    Keywords
    Antibiotics; Mutans streptococci; S. anginosus; Susceptibility

    Tables

    Table 1
    Bacteria strains used in this study

    Table 2
    Interpretive table for biotyping of mutans streptococci8, 9)

    Table 3
    Interpretive standards for dilution susceptibility testing11)

    Table 4
    Biochemical test of S. anginosus isolated on MSB agar

    Table 5
    Minimum inhibitory concentration of antibiotics against mutans streptococci and S. anginosus

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    MeSH Terms
    Amoxicillin
    Anti-Bacterial Agents
    Bacitracin
    Cefuroxime
    Ciprofloxacin
    Dental Plaque*
    Erythromycin
    Microbial Sensitivity Tests
    Penicillin G
    Penicillins
    Streptococcus anginosus*
    Streptococcus*
    Vancomycin
    Metrics
    Share
    Tables
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