Open Access, Peer-reviewed
pISSN 2287-2434
eISSN 2287-447X
    Asian Oncol Nurs. 2013 Dec;13(4):201-209. Korean.
    Published online Dec 31, 2013.
    https://doi.org/10.5388/aon.2013.13.4.201
    © 2013 Korean Oncology Nursing Society
    Original Article

    Factors Influencing Medication Adherence to Oral Anticancer Drugs

    Yeon Hee Lee, and Ihn Sook Jeong
      • College of Nursing, Pusan National University, Yangsan, Korea.
    • Address reprint requests to: Lee, Yeon Hee. College of Nursing, Pusan National University, Yangsan 626-870, Korea. Tel: +82-51-510-8318, Fax: +82-51-510-8308, Email: vandi@pusan.ac.kr
    Received October 15, 2013; Accepted December 10, 2013.

    This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

    Abstract

    Purpose

    The purpose of this study was to identify factors that influence on medication adherence to oral anticancer drugs.

    Methods

    147 cancer patients receiving oral anticancer drugs were surveyed. The survey content included medication adherence, social support, depression, self-efficacy and symptom experience.

    Results

    The mean medication adherence was 6.77 based on 8 points (84.6 based on 100 points). The influencing factors on medication adherence were symptom experience (β=-.19), decision of oral chemotherapy (β=.25) and social support (β=.21), and 17.0% of the variance in medication adherence was explained by these three factors in stepwise multiple regression analysis.

    Conclusion

    The level of medication adherence to oral anticancer drugs was relatively high, and increased by decreasing symptom experience, and increasing social support. Considering the medication adherence is related with positive treatment outcome, nursing effort to improve medication adherence by decreasing symptom experience, and increasing social support is needed.

    Keywords
    Mouth; Drug Therapy; Medication Adherence; Neoplasms

    Tables

    Table 1
    Level of Medication Adherence to Oral Chemotherapy (N=147)

    Table 2
    Medication Adherence by Socio-demographic and Disease-related Characteristics (N=147)

    Table 3
    Medication Adherence by Characteristics of Oral Chemotherapy (N=147)

    Table 4
    Correlation between Variables (N=147)

    Table 5
    Influencing Factors on Medication Adherence by Stepwise Multiple Regression (N=145)

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    MeSH Terms
    Depression
    Drug Therapy
    Humans
    Medication Adherence*
    Mouth
    Nursing
    Treatment Outcome
    Metrics
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