ABSTRACT

A herbomineral formulation was developed in suspension form by using the herb, mineral and different excipient and named “Alcecare”. The formulation was prepared by mixing calculated quantity of shatavari aqueous extract, fennel seed oil and praval bhasma to make smooth cream and then other excipients added to form a suspension for the evaluation of antiulcer activity in rats using aspirin model. The anti-ulcer activity of herbomineral formulation showed that the minimum ulcer index was observed with pantoprazole (1.98±0.29) which was nearly comparable with herbomineral formulation (2.85±0.47) and showed significant antiulcer activity compared to negative control with reducing the volume of gastric juice (5.99±0.25, 3.57±0.92, 4.22±0.67 of ulcerated control, standard and herbomineral formulation groups respectively). It was observed that developed herbomineral formulation possess significant antiulcer activity compared to control group and obtained results were nearly comparable with standard drug (pantoprazole).