FUKUSHIMA JOURNAL OF MEDICAL SCIENCE
Online ISSN : 2185-4610
Print ISSN : 0016-2590
ISSN-L : 0016-2590
Case report
Peripheral platelet phagocytosis in an extremely low birth weight infant:a case report
Daisuke Hatanaka, Kana Ito, Eisuke Fukama, Tomoaki Nomura, Michiko Kusakari, Hidehiro Takahashi, Toshihiko Nakamura, Naoto Takahashi
Author information
Keywords: extremely low birth weight infant, sepsis, thrombocytopenia, platelet phagocytosis, cytokine profile
JOURNAL OPEN ACCESS FULL-TEXT HTML

2022 Volume 68 Issue 2 Pages 129-134

Browse “Advance online publication” version
Details
Full-text HTML Download PDF (714K)
Download citation RIS

(compatible with EndNote, Reference Manager, ProCite, RefWorks)

BIB TEX

(compatible with BibDesk, LaTeX)

Text
How to download citation
Contact us
Abstract

A 768 g female neonate, born at 25 weeks’ gestation, developed sepsis due to methicillin-resistant Staphylococcus epidermidis on day 14. Severe thrombocytopenia was observed, and hemophagocytic macrophages were identified in her peripheral blood smear. Cytokine profiles at the time of onset suggested that an inflammatory cytokine storm had activated lymphocytes and macrophages, leading to platelet phagocytosis. After administration of vancomycin for 14 days and immunoglobulin therapy, she improved without any complications. Considering the results of cytokine profiles, early intervention for infection may have prevented progression to hemophagocytic lymphohistiocytosis and reduced the severity of clinical symptoms.

Content from these authors
© 2022 The Fukushima Society of Medical Science

This article is licensed under a Creative Commons [Attribution-NonCommercial-ShareAlike 4.0 International] license.
https://creativecommons.org/licenses/by-nc-sa/4.0/
Previous article Next article
Favorites & Alerts

Recently viewed articles
Share this page
feedback
 Top