Actinic Granuloma Developed in a Herpes Zoster Scar

Wolf's isotopic response describes the occurrence of a new, unrelated disease that appears at the location of a previously healed disease, most commonly herpes zoster. Several cutaneous reactions including granuloma annulare have been known to occur within resolved herpes zoster lesions. We report a case of actinic granuloma which developed on a site previously affected by herpes zoster, and is thought to be an isotopic response.