CC BY-NC-ND 4.0 · World J Nucl Med 2020; 19(02): 168-170
DOI: 10.4103/wjnm.WJNM_97_18
Case Report

Temporal muscle uptake causing an unusual focal artifact on three-dimensional stereotactic surface projections statistical maps of (18F) fluorodeoxyglucose brain positron emission tomography in a patient with Alzheimer's disease

Tanyaluck Thientunyakit
Department of Radiology, Division of Nuclear Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
,
Satoshi Minoshima
1   Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, Utah, USA
› Author Affiliations

Abstract

(18F) fluorodeoxyglucose brain positron emission tomography and statistical mapping analysis, such as three-dimensional stereotactic surface projections, have been used widely for the evaluation of dementia patients. We present an unusual focal artifact on the statistical maps resulting from intense temporal muscle uptake in a patient with Alzheimer's disease. Various degrees of physiologic uptake can be seen in head and neck muscles. However, it is unusual to see a focal artifact on the statistical maps due to temporal muscle uptake. This case illustrates the importance of quality control of imaging processing when atypical findings are seen on statistical maps.

Financial support and sponsorship

The research was partially supported by Siriraj Grant for Research Development and Faculty of Medicine Siriraj Hospital, Mahidol University.




Publication History

Received: 31 October 2018

Accepted: 09 November 2018

Article published online:
19 April 2022

© 2020. Sociedade Brasileira de Neurocirurgia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 
  • References

  • 1 Minoshima S, Frey KA, Koeppe RA, Foster NL, Kuhl DE. A diagnostic approach in Alzheimer's disease using three-dimensional stereotactic surface projections of fluorine-18-FDG PET. J Nucl Med 1995;36:1238-48.
  • 2 Karunanithi S, Soundararajan R, Sharma P, Naswa N, Bal C, Kumar R, et al. Spectrum of physiologic and pathologic skeletal muscle (18)F-FDG uptake on PET/CT. AJR Am J Roentgenol 2015;205:W141-9.
  • 3 Parida GK, Roy SG, Kumar R. FDG-PET/CT in skeletal muscle: Pitfalls and pathologies. Semin Nucl Med 2017;47:362-72.
  • 4 Bar-Shalom R. Muscle uptake of 18-fluorine fluorodeoxyglucose. Semin Nucl Med 2000;30:306-9.
  • 5 Barrington SF, Maisey MN. Skeletal muscle uptake of fluorine-18-FDG: Effect of oral diazepam. J Nucl Med 1996;37:1127-9.
  • 6 Abouzied MM, Crawford ES, Nabi HA. 18F-FDG imaging: Pitfalls and artifacts. J Nucl Med Technol 2005;33:145-55.
  • 7 Kostakoglu L, Wong JC, Barrington SF, Cronin BF, Dynes AM, Maisey MN, et al. Speech-related visualization of laryngeal muscles with fluorine-18-FDG. J Nucl Med 1996;37:1771-3.
  • 8 Jabour BA, Choi Y, Hoh CK, Rege SD, Soong JC, Lufkin RB, et al. Extracranial head and neck: PET imaging with 2-[F-18]fluoro-2-deoxy-D-glucose and MR imaging correlation. Radiology 1993;186:27-35.
  • 9 Cohade C, Osman M, Pannu HK, Wahl RL. Uptake in supraclavicular area fat (“USA-fat”): Description on 18F-FDG PET/CT. J Nucl Med 2003;44:170-6.
  • 10 Engel H, Steinert H, Buck A, Berthold T, Huch Böni RA, von Schulthess GK, et al. Whole-body PET: Physiological and artifactual fluorodeoxyglucose accumulations. J Nucl Med 1996;37:441-6.