CC BY-NC-ND 4.0 · Asian J Neurosurg 2020; 15(01): 210-213
DOI: 10.4103/ajns.AJNS_166_19
Case Report

Trans-nasal trans-sphenoidal endoscopic resection of spindle cell oncocytoma of adenohypophysis: The first case report in a child and a review of literature

Mohammad Samadian
Department of Neurosurgery, Loghman Hospital, Shahid Beheshti University of Medical Sciences, Tehran
,
Seyad Mousavinejad
Department of Neurosurgery, Loghman Hospital, Shahid Beheshti University of Medical Sciences, Tehran
,
Shahrokh Khoshsirat
1   Department of ENT, Skull Base Research Center, Loghman Hospital, Shahid Beheshti University of Medical Sciences, Tehran
,
Mahmood Dehghan
Department of Neurosurgery, Loghman Hospital, Shahid Beheshti University of Medical Sciences, Tehran
,
Guive Sharifi
Department of Neurosurgery, Loghman Hospital, Shahid Beheshti University of Medical Sciences, Tehran
,
Kaveh Ebrahimzadeh
Department of Neurosurgery, Loghman Hospital, Shahid Beheshti University of Medical Sciences, Tehran
,
Omidvar Rezaei
Department of Neurosurgery, Loghman Hospital, Shahid Beheshti University of Medical Sciences, Tehran
› Author Affiliations

Spindle cell oncocytoma (SCO) is a rare tumor of adenohypophysis, arising from the sellar region. So far, about 35 cases of SCO in the sellar region have been reported. In this report, we present the first case of pediatric SCO and review the literature concerning the tumor origin, clinical presentations, radiological features, and treatment modalities. An 8-year-old male was referred to our clinic with progressive visual loss in the left eye and headache over the past 6 months. Cranial magnetic resonance imaging revealed a solid adenohypophysis mass with suprasellar extension, as well as compression and displacement of the optic chiasm. The patient underwent endoscopic trans-sphenoidal resection of the tumor. The tumor was diagnosed as SCO based on the histological study. He did not receive radiation therapy. The patient's condition remained stable, with no radiological recurrence in the past follow-up 2 years after the surgery.

Financial support and sponsorship

Nil.




Publication History

Received: 06 June 2019

Accepted: 20 December 2019

Article published online:
16 August 2022

© 2020. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 
  • References

  • 1 Roncaroli F, Scheithauer BW, Cenacchi G, Horvath E, Kovacs K, Lloyd RV, et al. 'Spindle cell oncocytoma' of the adenohypophysis: A tumor of folliculostellate cells? Am J Surg Pathol 2002;26:1048-55.
  • 2 Matyja E, Maksymowicz M, Grajkowska W, Olszewski W, Zieliński G, Bonicki W. Spindle cell oncocytoma of the adenohypophysis – A clinicopathological and ultrastructural study of two cases. Folia Neuropathol 2010;48:175-84.
  • 3 Farooq MU, Bhatt A, Chang HT. Teaching neuroimage: Spindle cell oncocytoma of the pituitary gland. Neurology 2008;71:e3.
  • 4 Dekkers OM, Hammer S, de Keizer RJ, Roelfsema F, Schutte PJ, Smit JW, et al. The natural course of non-functioning pituitary macroadenomas. Eur J Endocrinol 2007;156:217-24.
  • 5 Dahiya S, Sarkar C, Hedley-Whyte ET, Sharma MC, Zervas NT, Sridhar E, et al. Spindle cell oncocytoma of the adenohypophysis: Report of two cases. Acta Neuropathol 2005;110:97-9.
  • 6 Kloub O, Perry A, Tu PH, Lipper M, Lopes MB. Spindle cell oncocytoma of the adenohypophysis: Report of two recurrent cases. Am J Surg Pathol 2005;29:247-53.
  • 7 Vajtai I, Sahli R, Kappeler A. Spindle cell oncocytoma of the adenohypophysis: Report of a case with a 16-year follow-up. Pathol Res Pract 2006;202:745-50.
  • 8 Borota OC, Scheithauer BW, Fougner SL, Hald JK, Ramm-Pettersen J, Bollerslev J. Spindle cell oncocytoma of the adenohypophysis: Report of a case with marked cellular atypia 2008;28:91-5.
  • 9 Coiré CI, Horvath E, Smyth HS, Kovacs K. Rapidly recurring folliculostellate cell tumor of the adenohypophysis with the morphology of a spindle cell oncocytoma: Case report with electron microscopic studies. Clin Neuropathol 2008;28:303-8.
  • 10 Demssie YN, Joseph J, Dawson T, Roberts G, de Carpentier J, Howell S. Recurrent spindle cell oncocytoma of the pituitary, a case report and review of literature. Pituitary 2011;14:367-70.
  • 11 Borges MT, Lillehei KO, Kleinschmidt-DeMasters BK. Spindle cell oncocytoma with late recurrence and unique neuroimaging characteristics due to recurrent subclinical intratumoral bleeding. J Neurooncol 2011;101:145-54.
  • 12 Mlika M, Azouz H, Chelly I, Saïd IB, Jemel H, Haouet S, et al. Spindle cell oncocytoma of the adenohypophysis in a woman: A case report and review of the literature. J Med Case Rep 2011;5:64.
  • 13 Romero-Rojas AE, Melo-Uribe MA, Barajas-Solano PA, Chinchilla-Olaya SI, Escobar LI, Hernandez-Walteros DM. Spindle cell oncocytoma of the adenohypophysis. Brain Tumor Pathol 2011;28:359-64.
  • 14 Ogiwara H, Dubner S, Shafizadeh S, Raizer J, Chandler JP. Spindle cell oncocytoma of the pituitary and pituicytoma: Two tumors mimicking pituitary adenoma. Surg Neurol Int 2011;2:116.
  • 15 Fujisawa H, Tohma Y, Muramatsu N, Kida S, Kaizaki Y, Tamamura H. Spindle cell oncocytoma of the adenohypophysis with marked hypervascularity. Case report. Neurol Med Chir (Tokyo) 2012;52:594-8.
  • 16 Alexandrescu S, Brown RE, Tandon N, Bhattacharjee MB. Neuron precursor features of spindle cell oncocytoma of adenohypophysis. Ann Clin Lab Sci 2012;42:123-9.
  • 17 Singh G, Agarwal S, Sharma MC, Suri V, Sarkar C, Garg A, et al. Spindle cell oncocytoma of the adenohypophysis: Report of a rare case and review of literature. Clin Neurol Neurosurg 2012;114:267-71.
  • 18 Rotman JA, Kucharczyk W, Zadeh G, Kiehl TR, Al-Ahmadi H. Spindle cell oncocytoma of the adenohypophysis: A case report illustrating its natural history with 8-year observation and a review of the literature. Clin Imaging 2014;38:499-504.
  • 19 Zygourakis CC, Rolston JD, Lee HS, Partow C, Kunwar S, Aghi MK. Pituicytomas and spindle cell oncocytomas: Modern case series from the University of California, San Francisco. Pituitary 2015;18:150-8.
  • 20 Mu Q, Yu J, Qu L, Hu X, Gao H, Liu P, et al. Spindle cell oncocytoma of the adenohypophysis: Two case reports and a review of the literature. Mol Med Rep 2015;12:871-6.
  • 21 Custodio PJP, Jho DH, Pu C, Gordon MB, Donangelo I. Spindle cell oncocytoma of the pituitary presenting with severe hyponatremia. AACE Clinical Case Reports 2016;2:e237-e43.
  • 22 Ryu WH, Hamilton L, Starreveld Y, Chan J. An unusual oncocytic sellar neoplasm in a patient with Birt-Hogg-Dubé syndrome. Int J Neuropathol 2015;3:43-54.
  • 23 Mansour M, Juanita G, Tyler S, Edison Valle, Shams H, Teresa A. RARE-08. Spindle cell oncocytoma od the pituitary gland: Case report and literature review. Neuro Oncol 2015;202:10-4.
  • 24 Vuong HG, Kondo T, Tran TM, Oishi N, Nakazawa T, Mochizuki K, et al. Spindle cell oncocytoma of adenohypophysis: Report of a case and immunohistochemical review of literature. Pathol Res Pract 2016;212:222-5.
  • 25 Osman M, Wild A. Spindle cell oncocytoma of the anterior pituitary presenting with an acute clinical course due to intraventricular hemorrhage. A case report and review of literature. Am J Case Rep 2017;18:894-901.
  • 26 Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, et al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 2007;114:97-109.
  • 27 Roncaroli F, Scheithauer BW. Papillary tumor of the pineal region and spindle cell oncocytoma of the pituitary: New tumor entities in the 2007 WHO Classification. Brain Pathol 2007;17:314-8.
  • 28 Hasiloglu ZI, Ure E, Comunoglu N, Tanriover N, Oz B, Gazioglu N, et al. New radiological clues in the diagnosis of spindle cell oncocytoma of the adenohypophysis. Clin Radiol 2016;71:937.e5-11.
  • 29 Kong X, Li D, Kong Y, Zhong D. Malignant adenohypophysis spindle cell oncocytoma with repeating recurrences and a high Ki-67 index. Medicine (Baltimore) 2017;96:e5657.