CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2011; 21(01): 34-37
DOI: 10.4103/0971-3026.76052
Chest

Case report: Pulmonary syphilis mimicking pulmonary hematogenous metastases on chest CT and integrated PET/CT

Hyung Jun Kim
Department of Radiology, Chonnam National University Hospital, Gwangju, South Korea
,
Hyun Ju Seon
Department of Radiology, Chonnam National University Hospital, Gwangju, South Korea
,
Hyo Hyun Shin
Department of Radiology, Chonnam National University Hospital, Gwangju, South Korea
,
Yoo-Duk Choi
Department of Pathology, Chonnam National University Hospital, Gwangju, South Korea
› Author Affiliations

Abstract

We report a case of syphilis with pulmonary involvement. Chest CT scan and 18 F-fluorodeoxyglucose (FDG) PET/CT showed multiple pulmonary nodules mimicking pulmonary hematogenous metastases. This was confirmed on follow-up images that showed therapeutic response to penicillin.



Publication History

Article published online:
31 July 2021

© 2011. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

Thieme Medical and Scientific Publishers Private Ltd.
A-12, Second Floor, Sector -2, NOIDA -201301, India

 
  • References

  • 1 McPhee SJ. Secondary syphilis: uncommon manifestations of a common disease. West J Med 1984;140:35-42.
  • 2 Clark EG, Danbolt N. The Oslo stuy of the natural course of untreated syphilis: An epidemiologic investigation based on a re-study of the Boeck-Bruusgaard material. Med Clin North Am 1964;48:613-23.
  • 3 Pariser H. Infectious syphilis. Med Clin North Am 1964;48:625-36.
  • 4 Coleman DL, McPhee SJ, Ross TF, Naughton JL. Secondary syphilis with pulmonary involvement. West J Med 1983;138:875-8.
  • 5 Olson AL, Gutman JA, Welsh CH. A 50-year-old man wth skin lesions and multiple pulmonary nodules. Chest 2004;125:2322-7.
  • 6 Geer LL, Warshauer DM, Delany DJ. Pulmonary nodule in secondary syphilis. Australas Radiol 1985;29:240-2.
  • 7 Howard CP. Pulmonary syphilis. Am J Syphilis 1924;8:1-33.
  • 8 Carrera JL. A pathologic study of the lungs in one hundred and fifty-two autopsy cases of syphilis. Am J Syphilis 1920;4:1-33.
  • 9 David G, Perpoint T, Boibieux A, Pialat JB, Salord H, Devouassoux M, et al. Secondary pulmonary syphilis: report of a likely case and literature review. Clin Infect Dis 2006;42:11-5.
  • 10 Fenton KA, Lowndes CM. Recent trends in the epidemiology of sexually transmitted infections in the European Union. Sex Transm Infect 2004;80:255-63.
  • 11 Imdahl A, Jenkner S, Brink I, Nitzsche E, Stoelben E, Moser E, et al. Validation of FDG positron emission tomography for differentiation of unknown pulmonary lesions. Eur J Cardiothorac Surg 2001;20:324-9.
  • 12 Gould MK, Maclean CC, Kuschner WG, Rydzak CE, Owens DK. Accuracy of positron emission tomography for diagnosis of pulmonary nodules and mass lesions: a meta-analysis. JAMA 2001;285:914-24.
  • 13 Kubota R, Yamada S, Kubota K, Ishiwata K, Tamahashi N, Ido T. Intratumoral distribution of fluorine-18-fluorodeoxyglucose in vivo: high accumulation in macrophages and granulation tissues studied by microautoradiography. J Nucl Med 1992;33:1972-80.
  • 14 Pruzzo R, Redondo F, Amaral H, Glasinovic E, Caviedes I, Glasinovic JC. Anal and rectal syphilis on F-18 FDG PET/CT. Clin Nucl Med 2008;33:809-10.
  • 15 Lin M, Darwish BS, Chu J. Neurosyphilitic gumma on F18-2-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography: an old disease investigated with a new technology. J Clin Neurosci 2009;16:410-2.