| The Heart Rate Response to Intravenous Atropine during Propofol or Enflurane Anesthesia. |
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Su Sang Jung, Ji Sung Kim, Keon Sik Kim, Ok Young Shin, Wha Ja Kang |
1Department of Anesthesiology and Pain Medicine, Bupyung Serim Hospital, Incheon, Korea.
2Department of Anesthesiology and Pain Medicine, College of Medicine, Kyung Hee University, Seoul, Korea. whakang@hotmail.com |
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| Abstract |
BACKGROUND
Propofol increases the risk of bradycardia compared with other anesthetics. This paper reports the heart rate response to intravenous atropine during propofol and enflurane anesthesia.
METHODS
Sixty patients undergoing a transabdominal hysterectomy under general anesthesia were randomly assigned to two groups: the propofol group and the enflurane group.
All the patients received midazolam 2 mg intramuscularly and were then anesthetized with propofol or enflurane. The blood pressure and heart rate were taken at 1 min intervals for 10 min after a bolus injection of atropine 5microgram/kg.
RESULTS
In the enflurane group, the systolic blood pressure and heart rate were increased significantly at 1, 2 and 3 min after the atropine injection (P<0.05). When the two groups were compared, the heart rate in the enflurane group was significantly higher at 1, 2 and 3 min after atropine injection than in the propofol group (P<0.05).
CONCLUSIONS
The heart rate response to intravenous atropine during propofol anesthesia is attenuated compared with enflurane anesthesia. |
| Key Words:
atropine; bradycardia; enflurane; heart rate; propofol |
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