https://doi.org/10.4081/monaldi.2022.2209

Short- and long-term oral steroid therapy in patients with asthma exacerbation

Vol. 93 No. 1 (2023)
Submitted: January 20, 2022
Accepted: May 17, 2022
Published: June 8, 2022
Corticosteroids, asthma, disease exacerbation, short-term course, long-term care
Abstract Views: 967
PDF: 245
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Authors

Mehmet Erdem Çakmak
mehmeterdemcakmak@gmail.com
https://orcid.org/0000-0001-7899-3004
Department of Allergy and Clinical Immunology, Başakşehir Çam ve Sakura City Hospital, Istanbul, Turkey.
Saltuk Buğra Kaya
https://orcid.org/0000-0002-3890-1299
Department of Allergy and Clinical Immunology, Erzurum Training and Research Hospital, Erzurum, Turkey, Turkey.
Özge Can Bostan
Department of Chest Diseases, Division of Allergy and Clinical Immunology, Hacettepe University, School of Medicine, Ankara, Turkey.
Ebru Damadoğlu
Department of Chest Diseases, Division of Allergy and Clinical Immunology, Hacettepe University, School of Medicine, Ankara, Turkey.
Gül Karakaya
https://orcid.org/0000-0002-7524-091X
Department of Chest Diseases, Division of Allergy and Clinical Immunology, Hacettepe University, School of Medicine, Ankara, Turkey.
Ali Fuat Kalyoncu
https://orcid.org/0000-0001-7475-3775
Department of Chest Diseases, Division of Allergy and Clinical Immunology, Hacettepe University, School of Medicine, Ankara, Turkey.

Steroids are frequently used for symptom control in cases of asthma exacerbation. The aim of this study was to compare the effect of short-term and long-term oral steroid therapy on symptom control in patients with asthma exacerbation. Patients that received short-term (<10 d) and long-term (≥10 d) oral steroid therapy during asthma exacerbation were compared retrospectively. A visual analog scale (VAS) for symptom severity was administered, and the asthma control test (ACT) and pulmonary function tests were performed before and after treatment. The study included 69 patients and the overall mean duration of steroid treatment was 9.57±3.58 d (range: 5-25 d). Mean duration of short-term and long-term steroid treatment was 6.54±0.99 d and 11.63±3.21 d, respectively. Serious side-effects were not observed following oral steroid therapy. Post the short- and long-term oral steroid therapy there were not any significant differences between the 2 groups in terms of ACT, FEV1 (forced expiratory volume 1), or VAS symptom scores. The findings show that in patients with mild asthma exacerbation short-term oral steroid therapy is as effective as long-term steroid therapy and can be safely used for symptom control during periods of mild asthma exacerbation.

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How to Cite

Çakmak, Mehmet Erdem, Saltuk Buğra Kaya, Özge Can Bostan, Ebru Damadoğlu, Gül Karakaya, and Ali Fuat Kalyoncu. 2022. “Short- and Long-Term Oral Steroid Therapy in Patients With Asthma Exacerbation”. Monaldi Archives for Chest Disease 93 (1). https://doi.org/10.4081/monaldi.2022.2209.
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