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Hematology Reports
Volume 4
Issue 2
10.4081/hr.2012.e6
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Hematology Reports is published by MDPI from Volume 14 Issue 1 (2022). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Case Report

A Case of Cutaneous Large B-Cell Lymphoma of the Legs Appearing as Chronic Venous Ulceration

by
Marta Carlesimo
,
Diego Orsini
*,
Alessanrdra Narcisi
,
Claudia Abruzzese
,
Giorgia Cortesi
,
Gabriella De Marco
and
Alfredo Rossi
Dermatology Unit, S.Andrea Hospital, Faculty of Medicine and Psychology, University of Rome Sapienza, Via di Grottarossa, 1035, 00189 Rome, Italy
*
Author to whom correspondence should be addressed.
Hematol. Rep. 2012, 4(2), e6; https://doi.org/10.4081/hr.2012.e6
Submission received: 5 August 2011 / Revised: 23 January 2012 / Accepted: 6 February 2012 / Published: 24 April 2012

Abstract

We report here a case of a woman with a cutaneous large B-cell lymphoma of the legs. She had a plaque lesion, superficially ulcerated and necrotized with tumorous borders situated on the posterior side of the right leg and two red or bluish-red nodular lesions. A skin biopsy from both nodular and plaque lesion showed a diffuse infiltrate of atypical large B cells CD20+ and CD79a+, spanning epidermis, dermis and subcutaneous tissue. A therapeutic approach containing anti-CD20 monoclonal antibody (rituximab) was suggested.
Keywords: primary cutaneous B cell lymphoma; B cell lymphoma of the leg; immunophenotype; therapy primary cutaneous B cell lymphoma; B cell lymphoma of the leg; immunophenotype; therapy

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MDPI and ACS Style

Carlesimo, M.; Orsini, D.; Narcisi, A.; Abruzzese, C.; Cortesi, G.; De Marco, G.; Rossi, A. A Case of Cutaneous Large B-Cell Lymphoma of the Legs Appearing as Chronic Venous Ulceration. Hematol. Rep. 2012, 4, e6. https://doi.org/10.4081/hr.2012.e6

AMA Style

Carlesimo M, Orsini D, Narcisi A, Abruzzese C, Cortesi G, De Marco G, Rossi A. A Case of Cutaneous Large B-Cell Lymphoma of the Legs Appearing as Chronic Venous Ulceration. Hematology Reports. 2012; 4(2):e6. https://doi.org/10.4081/hr.2012.e6

Chicago/Turabian Style

Carlesimo, Marta, Diego Orsini, Alessanrdra Narcisi, Claudia Abruzzese, Giorgia Cortesi, Gabriella De Marco, and Alfredo Rossi. 2012. "A Case of Cutaneous Large B-Cell Lymphoma of the Legs Appearing as Chronic Venous Ulceration" Hematology Reports 4, no. 2: e6. https://doi.org/10.4081/hr.2012.e6

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