Korean Circ J. 2005 May;35(5):345-352. English.
Published online May 31, 2005.
https://doi.org/10.4070/kcj.2005.35.5.345
Published online May 31, 2005.
https://doi.org/10.4070/kcj.2005.35.5.345
Copyright © 2005 The Korean Society of Circulation
Review
Gene Therapy for Heart Failure
Jang Whan Bae
and Myeong Chan Cho
Abstract
Heart failure is an important public medical problem in the developed countries. Although there are numerous and fascinating medicines given by physicians for the treatment of heart failure, the general 5 year survival rate for advanced heart failure is only about 50%. There are still many theoretical and practical problems to overcome before the application of gene therapy to cardiovascular disease becomes a reality in the future. With our increased knowledge on the development of gene delivery, vector systems, molecular basis of cardiac dysfunction, and the pathogenesis of heart failure at the cell level, gene therapy is emerging as a new therapeutic option for heart failure.
Keywords
Heart failure; Gene therapy; Vector
MeSH Terms
Permalink information copied to clipboard