Published online Dec 31, 1991.
https://doi.org/10.4070/kcj.1991.21.6.1219
Clinical Observation on Effect of Amlodipine in Angina Pectoris
Abstract
We evaluated the clinical effects of amlodipine in 10 patients(7 male and 3 female) with angina pectoris in terms of the effect on the anginal pain, hemodynamic changes and side effects.
The results obtained were as follows;
1) The clinical improvement was obsebed in 8(80.8%) of 10 and 9(88.9%) of 9 patients at 2 and 10 weeks after oral amlodipine.
2) The systolic and diastolic blood pressure was decreased significantly(136.0±16.5mmHg vs 117.0±10.6mmHg, p<0.01 and 85.0±9.7mmHg vs 75.0±5.3mmHg, p<0.01 respectively) but the heart rate was indepentent of amlodipine administration.
3) The adverse effects of amlodipine were as headache in 3, facial flushing in 3, palpitation, dizziness, urinary difficulty in 1 respectively and one of them discontinued amlodipine due to severe palpitation and facial flushing.
