Published online Feb 28, 2011.
https://doi.org/10.4048/jbc.2011.14.S.S64
Depressive Symptom-Related Factors in Patients with Breast Cancer
Abstract
Purpose
Patients with breast cancer are at risk for developing psychological distress and psychiatric disorders such as depression. The aim of this study was to assess the depressive symptom related factors in women with breast cancer.
Methods
A total of 211 patients with breast cancer who had undergone an operation within 5 years participated in this survey with consent. Depressive symptoms in patients were measured using the 21-item Beck Depression Inventory (BDI) questionnaire in the outpatient clinic and sociodemographic, clinicopathologic factors of the patients were analyzed with a BDI score. The patients were divided into group A (BDI<16, n=146) and group B (BDI≥16, n=65).
Results
The mean age of the patients was 49.2 years and the mean follow-up period was 22 months. In the univariate analyses, postmenopausal status (p=0.014), tumor size (p=0.023) and presence of progesterone receptor (p=0.012) were significantly associated with depressive symptom. In multivariate analysis, only postmenopause (p=0.021) and tumor size (p=0.018) were related with depressive symptom.
Conclusion
Depressive symptom is common in patients with breast cancer and a screening test for depression is needed in breast cancer patient who experienced menopause or has bigger tumor size.
Table 1
Sociodemographic factors associated with depressive symptom in breast cancer patients
Table 2
Clinicopathologic factors associated with depressive symptom in breast cancer patients
Table 3
Multivariate analysis for factors associated with depressive symptom in patients with breast cancer
References
-
Somerset W, Stout SC, Miller AH, Musselman D. Breast cancer and depression. Oncology (Williston Park) 2004;18:1021–1034.
-
-
Lee YH, Song JY. A study of the reliability and the validity of the BDI, SDS, and MMPI-D scales. Korean J Clin Psychol 1991;10:98–113.
-
-
Shin MS, Kim JS, Park KB. The cut-off score for the Korean version of Beck Depression Inventory. Korean J Clin Psychol 1993;12:71–81.
-
-
Rush AJ. The varied clinical presentations of major depressive disorder. J Clin Psychiatry 2007;68 Suppl 8:4–10.
-
-
Kim SW, Kim SY, Kim JM, Park MH, Yoon JH, Shin IS, et al. Use of antidepressants in patients with breast cancer. Korean J Psychopharmacol 2009;20:63–77.
-
-
Aragona M, Muscatello MR, Mesiti M. Depressive mood disorders in patients with operable breast cancer. J Exp Clin Cancer Res 1997;16:111–118.
-
-
Toney SD. Identifying and managing depression in women. J Manag Care Pharm 2007;13 9 Suppl A:S16–S22.
-