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Mechanical Strength Properties of Injectable Carbonate Apatite Cement with Various Concentration of Sodium Carboxymethyl Cellulose
Abstract:
Mechanical strength is one of the key factors for clinical application of injectable carbonate apatite (CO3Ap) cement. Incorporation of polymeric additives into the mixing liquid of injectable bone cement has been known to improve cement injectability. The aim of this study is to determine whether incorporation of sodium carboxymethyl cellulose (Na CMC) into the mixing liquid would affect the diametral tensile strength (DTS) of injectable CO3Ap cement. In the present study, Na CMC, a polymeric additive and a cellulose derivative, was used to promote the injectability of CO3Ap cement. Three groups of CO3Ap cement samples consist of CaCO3 and CaHPO4 powder in each group were mixed with 0.5 %, 1%, and 2% Na CMC solution incorporated to 0.2 mol/L Na2HPO4 solution. As a control, powder mixed with 0.2 mol/L Na2HPO4 solution was used. Samples were kept in an incubator (37°C, 100% relative humidity, 24 hours). The mechanical strength properties were evaluated by diametral tensile strength (DTS). The average DTS of samples containing 0.5%, 1%, and 2% Na CMC were 3.19 MPa, 3.57 MPa, and 3.06 MPa, respectively. While the average DTS of the control group was 3.29 MPa. The groups containing Na CMC in all concentrations showed no statistical difference (p>0.05) on DTS compared to the control group. The injectability improved as the concentration of Na CMC increased. In conclusion, revealed that Na CMC does not affect the mechanical strength of CO3Ap cement. Therefore, it may be considered as an effective material to promote cement injectability. Further study of additives that can be used to promote the injectability of CO3Ap cement and enhance the mechanical strength awaits based on this initial finding.
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Pages:
56-60
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Online since:
November 2017
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