Polyethylene Glycol and Polyethylene Glycol/Hydroxyapatite Constructs Produced through Stereo-Thermal Lithography

Article Preview

Abstract:

Stereo-thermal lithography (STLG) is an innovative system that uses ultraviolet (UV) radiation and near-infrared (IR) radiation simultaneously to initiate the curing reaction in a liquid solution, containing both UV and IR photoinitiator. In this research work, poly (ethylene glycol) dimethacrylate (PEGDMA) and PEGDMA/hydroxyapatite (HA) constructs were produced using the STLG system, operating in the UV mode, and characterised regarding the morphology and water absorption properties. Constructs were produced with different geometries and shapes by introducing several variations in the processing parameters, such as the irradiation time and the layer thickness. Results show the ability of the system to produce constructs at the micro-scale with very good definition and resolution. The irradiation time is the critical processing parameter, strongly affecting the water absorption and the structural integrity of the constructs.

You might also be interested in these eBooks

Info:

Periodical:

Pages:

87-92

Citation:

Online since:

August 2013

Export:

Price:

[1] F.P.W. Melchels, M.A.N. Domingos, T.J. Klein, J. Malda, P.J. Bártolo and D.W. Hutmacher: Prog Polym Sci. Vol. 37 (2012), pp.1079-1104.

Google Scholar

[2] P. Bártolo, J.P. Kruth, J. Silva, G. Levy, A. Malshe, K. Rajurkar, M. Mitsuishi, J. Ciurana and M. Leu: CIRP Ann Manuf Technol, Vol. 61 (2012), pp.635-655.

DOI: 10.1016/j.cirp.2012.05.005

Google Scholar

[3] P.J. Bártolo, M. Domingos, T. Patrício, S. Cometa and V. Mironov in: Advances on Modeling in Tissue Engineering, edited by P.R. Fernandes and P.J. Bártolo, Springer, (2011), pp.137-176.

DOI: 10.1007/978-94-007-1254-6_8

Google Scholar

[4] J.M. Matias, P.J. Bártolo and A.V. Pontes: J App Pol Sci, Vol. 114 (2009), pp.3673-3685.

Google Scholar

[5] P.J. Bártolo: Int J Adv Manuf Techn., Vol. 32 (2007), pp.480-491.

Google Scholar

[6] T.M. Seck, F.P.W. Melchels, J. Feijen and D.W. Grijpma: J Contr Rel., Vol. 148 (2010), pp.34-41.

Google Scholar

[7] F.P.W. Melchels, J. Feijen and D.W. Grijpma: Biomaterials, Vol. 30 (2009), pp.3801-3809.

Google Scholar

[8] P. Zorlutuna, J.H. Jeong, H. Kong and R. Bashir: Adv Funct Mat, Vol. 21 (2011), pp.3642-3651.

Google Scholar

[9] V. Chan, P. Zorlutuna, J.H. Jeong, H. Kong and R. Bashir: Lab Chip, Vol. 10 (2010), p.2062-(2070).

Google Scholar

[10] F.P.W. Melchels, J. Feijen, D.W. Grijpma: Biomaterials, Vol. 31 (2010), pp.6121-6130.

DOI: 10.1016/j.biomaterials.2010.04.050

Google Scholar

[11] P.J. Bártolo and G. Mitchell: Rap Prot J, Vol. 9 (2003), pp.150-156.

Google Scholar

[12] P.J. Bártolo (2001) Optical approaches for macroscopic and microscopic engineering, PhD Thesis, University of Reading, UK.

Google Scholar