Effect of Polyvinyl Alcohol Concentration on the Mechanical Properties of Collagen/Polyvinyl Alcohol Blends

Jan Vesely; Lukas Horny; Hynek Chlup; Milos Beran; Milan Krajicek; Rudolf Zitny

doi:10.4028/www.scientific.net/AMM.732.161

Paper Titles

Experimental Study of Mechanical Behavior of HPL Composites
p.139

Stress-Controlled Fatigue Testing of E-Glass Epoxy Composite: Monitoring of Micro-Damage
p.143

Characteristics of PU Foam at Long Term Static and Dynamic Loading
p.149

About the Verification of External Fixators Applied in Traumatology and Orthopaedics
p.153

Effect of Polyvinyl Alcohol Concentration on the Mechanical Properties of Collagen/Polyvinyl Alcohol Blends
p.161

FEM Modelling and Experimental Analysis of Mechanical Properties of Artificial Blood Vessel
p.165

Estimation of Crack Depth and Profile Using DCPD Method in Full Scale Railway Axle Loaded by Rotating Bending
p.171

Static and Dynamic Experimental Stress-Strain Analysis of Axles Loaded by Rotation Bending
p.175

The Influence of Facet Size and Filtering on the Results of Strain Fields’ Investigation Performed on Small Surfaces Using Digital Image Correlation
p.179

HomeApplied Mechanics and MaterialsApplied Mechanics and Materials Vol. 732Effect of Polyvinyl Alcohol Concentration on the...

Effect of Polyvinyl Alcohol Concentration on the Mechanical Properties of Collagen/Polyvinyl Alcohol Blends

Abstract:

The effects of the polyvinyl alcohol (PVA) concentration on mechanical properties of hydrogels based on blends of native or denatured collagen / PVA were examined. Blends of PVA with collagen were obtained by mixing the solutions in different ratios, using glycerol as a plasticizer. The solutions were cast on polystyrene plates and the solvent was allowed to evaporate at room temperature. Uniaxial tensile tests were performed in order to obtain the initial modulus of elasticity (up to deformation 0.1), the ultimate tensile stress and the deformation at failure of the material in the water-saturated hydrogel form. It was found that the material was elastic and the addition of PVA helped to enhance both the ultimate tensile stress and modulus of elasticity of the films. Samples prepared from denaturated collagen showed the higher ultimate tensile stress and the deformation at failure in comparison with those prepared from native collagen. The results suggest that we could expect successful application of the collagen/PVA biomaterial for tissue engineering.

You might also be interested in these eBooks

Applied Methods of the Analysis of Static and Dynamic Loads of Structures and Machines

View Preview

Info:

Periodical:

Applied Mechanics and Materials (Volume 732)

Pages:

161-164

DOI:

https://doi.org/10.4028/www.scientific.net/AMM.732.161

Citation:

Cite this paper

Online since:

February 2015

Authors:

Jan Vesely*, Lukas Horny, Hynek Chlup, Milos Beran, Milan Krajicek, Rudolf Zitny

Keywords:

Collagen, Polyvinyl Alcohol, Stress-Strain Analysis

Export:

RIS, BibTeX

Price:

Permissions:

Request Permissions

* - Corresponding Author

References

[1] R.Y. Kannan, H.J. Salacinski, K. Sales, P. Butler, A.M. Seifalian, The roles of tissue engineering and vascularisation in the development of micro-vascular networks: A review, Biomaterials 26 (2005) 1857-1875.

DOI: 10.1016/j.biomaterials.2004.07.006

Google Scholar

[2] B. Sarti, M. Scandola, Viscoelastic and thermal properties of collagen/poly(vinyl alcohol) blends, Biomaterials 16 (1995) 785-792.

DOI: 10.1016/0142-9612(95)99641-x

Google Scholar

[3] P. Giusti, L. Lazzeri, S. De Petris, M. Palla, M.G. Cascone, Collagen-based new bioartificial polymeric materials, Biomaterials 15 (1994) 1229-1233.

DOI: 10.1016/0142-9612(94)90274-7

Google Scholar

[4] C.A. Scotchford, M.G. Cascone, S. Downes, P. Giusti, Osteoblast responses to collagen-PVA bioartificial polymers in vitro: The effects of cross-linking method and collagen content, Biomaterials 19 (1998) 1-11.

DOI: 10.1016/s0142-9612(97)00236-6

Google Scholar

[5] C. Liu, Z. Xia, J.T. Czernuszka, Design and development of three-dimensional scaffolds for tissue engineering, Chemical Engineering Research and Design 85 (2007) 1051-1064.

DOI: 10.1205/cherd06196

Google Scholar