Cytocompatiblity of Ceramic Nanoparticles to Various Types of Cells

Shigeaki Abe; Nobuki Iwadera; Mami Mutoh; Tomohiko Katsurayama; Shino Morimoto; Ko Nakanishi; Tsukasa Akasaka; Satoshi Inoue; Yasutaka Yawaka; Junichiro Iida; Yasuhiro Yoshida

doi:10.4028/www.scientific.net/KEM.696.234

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In Vivo Evaluation of Zinc-Containing Nanostructured Carbonated Hydroxyapatite
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Studies on Connexin 43, a Gap-Junction Protein, in P19 Embryonal Carcinoma Cells after Culture on an Apatite Fiber Scaffold
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Cytocompatiblity of Ceramic Nanoparticles to Various Types of Cells
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Bioceramic Drug Delivery System for Cancer Treatment and Regenerative Medicine
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HomeKey Engineering MaterialsKey Engineering Materials Vol. 696Cytocompatiblity of Ceramic Nanoparticles to...

Cytocompatiblity of Ceramic Nanoparticles to Various Types of Cells

Abstract:

In this study, we investigated the cytocompatibility of ceramic nanoparticles on different types of cells. All ceramics nanoparticles investigated in this study except Copper oxide (CuO) exhibited good cytocompatibility and cell viability (90% or more) even at 20 ppm concentration. In contrast, CuO nanoparticles caused cell inflammation, and their effect depended on their particle size. Confocal fluorescence microscopy measurements indicated that some particles had penetrated into the cells. These results indicate that except CuO nanoparticles, all other ceramic nanoparticles reported herein exhibited excellent cytocompatibility even for lung epithelial cells.

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Periodical:

Key Engineering Materials (Volume 696)

Pages:

234-237

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.696.234

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Online since:

May 2016

Authors:

Shigeaki Abe*, Nobuki Iwadera, Mami Mutoh, Tomohiko Katsurayama, Shino Morimoto, Ko Nakanishi, Tsukasa Akasaka, Satoshi Inoue, Yasutaka Yawaka, Junichiro Iida, Yasuhiro Yoshida

Keywords:

Ceramic Nanoparticles, Cytocompatibility, Size Effect

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References

[1] F. Winnik, and D. Maysinger, Accounts Chem. Res., 46, 672-680 (2013).

Google Scholar

[2] A. Gajewicz, B. Rasulev, T. Dinadayalane, P. Urbaszek, T. Puzyn, D. Leszczynska, J. Leszczynski, Adv. Drug Del. Rev., 64, 1663-1693 (2012).

Google Scholar

[3] G. Hodes, Adv. Mater., 19, 639-655 (2007).

Google Scholar

[4] C. Burda, X. Chen, and R. Narayanan, M. A. El-Sayed, Chem. Rev., 105, 1025-1102 (2005).

Google Scholar

[5] H. Karlsson, P. Cronholm, J. Gustafsson, L. Moller, Chem. Res. Toxicol., 21, 1726-1732 (2008).

Google Scholar

[6] M. Tarantola, A. Pietuch, D. Schneider, J. Rother, E. Sunnick, C. Rosman, S. Pierrat, C. Sonnichsen, J. Wegener, and A. Janshoff, Nanotoxicol. 5, 254 (2011).

DOI: 10.3109/17435390.2010.528847

Google Scholar

[7] F. Watari, N. Takashi, A. Yokoyama, M. Uo, T. Akasaka, Y. Sato, S. Abe, Y. Totsuka, and K, Tohji, J. Royal Soc. Interface 6, S371 (2009).

DOI: 10.1098/rsif.2008.0488.focus

Google Scholar

[8] S. Abe, N. Iwadera, M. Esaki, I. Kida, M. Mutoh, T. Akasaka, M. Uo, Y. Yawaka, M. Morita, K. Haneda, T. Yonezawa, and F. Watari, Materials Science and Engineering 18, 192013 (2011).

DOI: 10.1088/1757-899x/18/19/192013

Google Scholar

[9] H. Shi, T. Zhang and H. Wang, J. Rare Earths, 29, 746752(2011).

Google Scholar

[10] N. Iwadera1, S. Abe, T. Akasaka, Y. Yawaka, and F. Watari, Key Engineering Materials, 529-530, 374-378 (2013).

DOI: 10.4028/www.scientific.net/kem.529-530.374

Google Scholar

[11] E. Seitoku, S. Abe, T. Kusaka, M. Nakamura, S. Inoue, Y. Yoshida, and H. Sano, J. Nanoscience and Nanotechnology, (in press).

Google Scholar