Dissolution Behavior of Submicron Biphasic Tricalcium Phosphate Powders

Rui Bing Wang; Wen Jian Weng; Xu Liang Deng; Kui Cheng; Xing Gang Liu; Pi Yi Du; Ge Shen; Gao Rong Han

doi:10.4028/www.scientific.net/KEM.309-311.223

Paper Titles

Osteoblastic Response to Resorbed Ceramic Surfaces; The Role of the Osteoclast in Osteoconduction
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Biodegradation and Characterization of Phase Separated NaCa(PO₃)₃ and KCa(PO₃)₃ from Pure Ca(PO₃)₂
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Enhancing Bone Regeneration by Synthetic Peptide-Coated CMP Granules
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Preparation of Submicron Biphasic α-TCP/HA Powders
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Dissolution Behavior of Submicron Biphasic Tricalcium Phosphate Powders
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Comparative Study of the Degradation Behavior of Mechanically Mixed and Chemically Precipitated Biphasic Calcium Phosphates
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Stress Analysis and Optimizing of Osteoinductive Ca-P Ceramics and Net-Cage-Structured Titanium Alloy in Dog Segmental Femoral Defect Reparation
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Effect of the Concentrations of the Starting Solution on the Syntheses and Powder Properties of Hollow Tricalcium-Phosphate Microspheres by Ultrasonic Spray-Pyrolysis Technique
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Solubility of Magnesium-Containing β-Tricalcium Phosphate: Comparison with that of Zinc-Containing β-Tricalcium Phosphate
p.239

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Dissolution Behavior of Submicron Biphasic Tricalcium Phosphate Powders

Abstract:

Submicron α-tricalcium phosphate (α-TCP), β-tricalcium phosphate (β-TCP) and biphasic α/β-TCP powders were prepared by an amorphous calcium phosphate (ACP) precursor way. For the biphasic TCP powders, primary particle size was 300nm, α-TCP and β-TCP primary particles were homogeneously mixed in the submicron powders. When the TCP powders were soaked in acetate buffer solution with pH 5, the Ca ion concentration in the soaked solutions and the resulting morphology variations were measured and observed. The results showed that the dissolution behavior of the biphasic TCP powders was different from α-TCP and β-TCP, and had a higher dissolved Ca ion concentration. This is attributed to a high supersaturation which is cased by the distribution homogeneity of two phase primary particles in submicron powders. These demonstrate the biphasic TCP to have potential to extend biological applications of Ca phosphates.