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Glucose Biosensor Based on Pt Nanoparticles/Graphene Chitosan Bionanocomposites

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Abstract:

In this paper, we fabricated a bionanocomposite film of glucose oxidase/Pt nanoparticles/graphene-chitosan (GOD/PtNPs/GR-Chit) for glucose sensing. The hybrid bionanocomposites modified GCE were characterized by scanning electron microscopy (SEM), cyclic voltammetry, and amperometric i-t curve. It was found that the PtNPs were uniformly deposited on the surface of GR-Chit hybrid film. The resultant PtNPs/GR-Chit/GCE exhibited a high electrochemical catalytic ability to hydrogen peroxide (H2O2), due to the electrocatalytic synergy of GR and PtNPs. The redox behavior of the GOD/PtNPs/GR-Chit/GCE is a surface-controlled process. Finally, we obtained the amperometric response of the GOD/PtNPs/GR-Chit/GCE toward different concentration of glucose, and also achieved a sensitive glucose oxidase biosensor with a detection limit of 4.6μM glucose.

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Info:

Periodical:

Applied Mechanics and Materials (Volume 328)

Pages:

695-699

DOI:

https://doi.org/10.4028/www.scientific.net/AMM.328.695

Citation:

Cite this paper

Online since:

June 2013

Authors:

Hui Ping Liu, Gong Yong Zhan, Qi Zhi Dong, Yan An Lv, Jian Fang Wang, Cheng An Tao, Zhi Hong Hu

Keywords:

Bionanocomposites, Glucose Biosensor, Graphene (GR), Pt Nanoparticle

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