Antioxidant Properties of Underutilized Bornean Dabai Fruit and its Potential Applications as a Nutraceutical Product

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Abstract:

It is no doubt that plants are a vital centerpiece and contributed immensely in the health care industry. Besides, it has been found that the indigenous people in developing countries had long been using local traditional plants for the treatment of diseases. The traditional plants are highly valued for their bioactive compounds which exhibits high antioxidant activity and has the potential in bringing down the risk of diseases. Canarium odontophyllum, also called dabai is one of the underutilized traditional plants consumed by the indigenous people in Borneo Island. The objective of this research is to characterize the antioxidant activity, metal chelating activity, the hydroxyl radical scavenging activity and identifying the potential bioactive compounds of dabai. The antioxidant, metal chelating and hydroxyl radical scavenging activity of dabai extract was evaluated using 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, Fe2+ chelating assay and the hydroxyl radical scavenging assay and found that it yielded an inhibition of 2.31%, 4.89% and 13.06% respectively. Then, chracterization using FTIR revealed the presence of flavonoids, anthocyanins and phenols serving as the potential bioactive compounds for the antioxidant activities. The knowledge gained from the antioxidant capacities and properties of dabai extract are potentially useful for the application of traditional plant medicine as an alternative nutraceutical product in the modern medical industry.

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Periodical:

Materials Science Forum (Volume 1077)

Pages:

211-218

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Online since:

December 2022

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* - Corresponding Author

[1] Kffuri CW, Lopes MA, Ming LC, Odonne G, Kinupp VF. Antimalarial plants used by indigenous people of the Upper Rio Negro in Amazonas, Brazil. Journal of Ethnopharmacology. 2016;178:188-98.

DOI: 10.1016/j.jep.2015.11.048

Google Scholar

[2] Shamsudin R, Ariffin SH, Zainol @ Abdullah WN, Azmi NS, Abdul Halim AA. Modelling the Kinetics of Color and Texture Changes of Dabai (Canarium odontophyllum Miq.) during Blanching. Agronomy. 2021;11(11).

DOI: 10.3390/agronomy11112185

Google Scholar

[3] Abdul Fattah Ab R, Mohd Zahid A, Norhasmillah Abu H, Josephine Anak E, Mohd Syafiq A, Ashraf AR, et al. The impact of (Canarium Odontophyllum Miq.) Dabai Optimum Soaking Condition Towards the Development of Dabai Peanut Spread Physicochemical Properties and Sensory Evaluation. Journal Of Agrobiotechnology. 2021;12(2).

DOI: 10.37231/jab.2021.12.2.258

Google Scholar

[4] Jelani N, Azlan A, A I, Khoo HE, muhammad alinafiah S. Fatty acid profiles and antioxidant properties of dabai oil. ScienceAsia. 2017;43:347.

DOI: 10.2306/scienceasia1513-1874.2017.43.347

Google Scholar

[5] Jelani A, Azlan A, Khoo HE, Razman M. Fatty acid profile and antioxidant properties of oils extracted from dabai pulp using supercritical carbon dioxide extraction. International Food Research Journal. 2019;26:1587-98.

Google Scholar

[6] Hanim F, Prasad K, A I, Yuon L, Azlan A. Antioxidant capacity of underutilized Malaysian Canarium odontophyllum (dabai) Miq. fruit. Journal of Food Composition and Analysis. 2010; 23: 777-81.

DOI: 10.1016/j.jfca.2010.04.008

Google Scholar

[7] Gülçin I, Alwasel S. Metal Ions, Metal Chelators and Metal Chelating Assay as Antioxidant Method. Processes. 2022;10:132.

DOI: 10.3390/pr10010132

Google Scholar

[8] Mohammed HH, Laftah WA, Noel Ibrahim A, Che Yunus MA. Extraction of essential oil from Zingiber officinale and statistical optimization of process parameters. RSC Advances. 2022; 12(8): 4843-51.

DOI: 10.1039/d1ra06711g

Google Scholar

[9] Brand-Williams W, Cuvelier ME, Berset C. Use of a free radical method to evaluate antioxidant activity. LWT - Food Science and Technology. 1995;28(1):25-30.

DOI: 10.1016/s0023-6438(95)80008-5

Google Scholar

[10] 1. Geng M, Ren M, Liu Z, Shang X. Free radical scavenging activities of pigment extract from Hibiscus syriacus L. petals in vitro. African Journal of Biotechnology. 2012;11:429-35.

DOI: 10.5897/ajb11.3037

Google Scholar

[11] Naithani V, Singhal AK, Chaudhary M. Comparative evaluation of Metal Chelating, Antioxidant and Free Radical Scavenging activity of TROIS and six products commonly used to control pain and inflammation associated with Arthritis. Int Drug Dev Res. 2011;3:208-16.

Google Scholar

[12] Pizzino G, Irrera N, Cucinotta M, Pallio G, Mannino F, Arcoraci V, et al. Oxidative Stress: Harms and Benefits for Human Health. Oxidative medicine and cellular longevity. 2017; 2017: 8416763-.

DOI: 10.1155/2017/8416763

Google Scholar

[13] Sharifi-Rad M, Anil Kumar NV, Zucca P, Varoni EM, Dini L, Panzarini E, et al. Lifestyle, Oxidative Stress, and Antioxidants: Back and Forth in the Pathophysiology of Chronic Diseases. Frontiers in Physiology. 2020;11.

DOI: 10.3389/fphys.2020.00694

Google Scholar

[14] Akar Z, Küçük M, Doğan H. A new colorimetric DPPH(•) scavenging activity method with no need for a spectrophotometer applied on synthetic and natural antioxidants and medicinal herbs. J Enzyme Inhib Med Chem. 2017;32(1):640-7.

DOI: 10.1080/14756366.2017.1284068

Google Scholar

[15] Treml J, Šmejkal K. Flavonoids as Potent Scavengers of Hydroxyl Radicals. Comprehensive Reviews in Food Science and Food Safety. 2016;15(4):720-38.

DOI: 10.1111/1541-4337.12204

Google Scholar

[16] Martemucci G, Costagliola C, Mariano M, D'andrea L, Napolitano P, D'Alessandro AG. Free Radical Properties, Source and Targets, Antioxidant Consumption and Health. Oxygen. 2022;2(2).

DOI: 10.3390/oxygen2020006

Google Scholar

[17] Tvrdá E, Benko F. Chapter 1 - Free radicals: what they are and what they do. In: Preedy VR, editor. Pathology: Academic Press; 2020. pp.3-13.

DOI: 10.1016/b978-0-12-815972-9.00001-9

Google Scholar

[18] Reis J, Silva Monteiro VV, De Souza Gomes R, do Carmo M, Vilhena G, Ribera P, et al. Action mechanism and cardiovascular effect of anthocyanins: A systematic review of animal and human studies. Journal of Translational Medicine. 2016;14:315.

DOI: 10.1186/s12967-016-1076-5

Google Scholar

[19] Khoo HE, Azlan A, A I, Abas F, Hamid M. Inhibition of Oxidative Stress and Lipid Peroxidation by Anthocyanins from Defatted Canarium odontophyllum Pericarp and Peel Using In Vitro Bioassays. PLoS One. 2014;9:e81447.

DOI: 10.1371/journal.pone.0081447

Google Scholar

[20] Oboh G, Odubanjo VO, Bello F, Ademosun AO, Oyeleye SI, Nwanna EE, et al. Aqueous extracts of avocado pear (Persea americana Mill.) leaves and seeds exhibit anti-cholinesterases and antioxidant activities in vitro. Journal of Basic and Clinical Physiology and Pharmacology. 2016; 27(2): 131-40.

DOI: 10.1515/jbcpp-2015-0049

Google Scholar

[21] Dehariya R, Chandrakar J, Dubey S, Ojha K, Dixit A. Scavenging and metal chelating potential of Carthamus tinctorius L. extracts. Current Botany. 2020:43-50.

DOI: 10.25081/cb.2020.v11.6009

Google Scholar

[22] Lei K, Wei W, Liu S, Zhou M, Lin X, Cao X. In Vitro Antioxidant Activity of the Anthocyanins in Sageretia Theezans Brongn Fruit. International Journal of Food Properties. 2015;19:150730061905006.

DOI: 10.1080/10942912.2015.1022261

Google Scholar

[23] Collin F. Chemical Basis of Reactive Oxygen Species Reactivity and Involvement in Neurodegenerative Diseases. Int J Mol Sci. 2019;20(10).

DOI: 10.3390/ijms20102407

Google Scholar

[24] Ivanova A, Gerasimova E, Gazizullina E. Study of Antioxidant Properties of Agents from the Perspective of Their Action Mechanisms. Molecules. 2020;25(18):4251.

DOI: 10.3390/molecules25184251

Google Scholar

[25] Dangles O. Antioxidant Activity of Plant Phenols: Chemical Mechanisms and Biological Significance. Current Organic Chemistry. 2012;16:692-714.

DOI: 10.2174/138527212799957995

Google Scholar

[26] Selen isbilir S, Orak H, Yagar H, Ekinci N. Determination of antioxidant activities of strawberry tree (Arbutus unedo L.) flowers and fruits at different ripening stages. Acta Scientiarum Polonorum, Hortorum Cultus. 2012;11.

DOI: 10.1007/s10068-011-0172-9

Google Scholar

[27] Pervin M, Hasnat MA, Lee Y, Kim D, Jo J, Lim B. Antioxidant Activity and Acetylcholinesterase Inhibition of Grape Skin Anthocyanin (GSA). Molecules. 2014;19.

DOI: 10.3390/molecules19079403

Google Scholar

[28] Chew LY, Khoo HE, A I, Azlan A, Lau C. Analysis of Phenolic Compounds of Dabai (Canarium odontophyllum Miq.) Fruits by High-Performance Liquid Chromatography. Food Analytical Methods. 2011;5:126-37.

DOI: 10.1007/s12161-011-9217-1

Google Scholar

[29] Rudrapal M, Khairnar SJ, Khan J, Dukhyil AB, Ansari MA, Alomary MN, et al. Dietary Polyphenols and Their Role in Oxidative Stress-Induced Human Diseases: Insights Into Protective Effects, Antioxidant Potentials and Mechanism(s) of Action. Front Pharmacol. 2022;13.

DOI: 10.3389/fphar.2022.806470

Google Scholar