Infect Chemother. 2012 Dec;44(6):454-457. Korean.
Published online Dec 31, 2012.
Copyright © 2012 by The Korean Society of Infectious Diseases and Korean Society for Chemotherapy
Case Report

Case of Hemorrhagic Fever with Renal Syndrome in Jeju Island

Chae Moon Lim,1 Sang Taek Heo,1 Jinseok Kim,1 Jung Re Yu,1 Young Ree Kim,2,4 and Keun Hwa Lee3,4
    • 1Department of Internal Medicine, Jeju National University School of Medicine, Jeju, Korea.
    • 2Department of Laboratory Medicine, Jeju National University School of Medicine, Jeju, Korea.
    • 3Department of Microbiology and Immunology, Jeju National University School of Medicine, Jeju, Korea.
    • 4The Environ-Mental Health Center, Jeju National University School of Medicine, Jeju, Korea.
Received March 06, 2012; Revised June 07, 2012; Accepted June 07, 2012.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Hemorrhagic fever with renal syndrome (HFRS) caused by the Hantann virus occurs frequently in Korea. On the other hand, the incidence of HFRS is very low in Jeju Island. A 62-year-old man was transferred from another hospital because of persistent fever, myalgia, generalized edema, epigastric pain, conjunctival injection, costovertebral angle tenderness, thrombocytopenia and azotemia. On the second hospital day, he exhibited oliguric symptoms. His urine output increased from the fourth hospital day. The test for the anti-Hantaan virus antibody was positive. Finally, he was diagnosed with HFRS and recovered with conservative management. HFRS should be considered when acute renal failure develops in patients with fever and thrombocytopenia in Jeju Island.

Keywords
Hemorrhagic fever with renal syndrome; Hantavirus; Jeju; Crocidura shantungenesis

References

    1. Jun DW, Cho KR, Kim SM, Kahang KW, Kim HJ, Kang CM, Park CH. Clinical features of hemorrhagic fever with renal syndrome in civilian. Korean J Nephrol 2000;19:70–76.
    1. Kim HY. Hemorrhagic fever with renal syndrome. Infect Chemother 2009;41:323–332.
    1. Noh YT, Cho JE, Han MG, Lee NY, Kim SY, Chu C, Lee HD, Nam JH, Park KY, Shin YH, Cho HW, Song HJ, Ju YR. Seroepidemiological characteristics of haemorrhagic fever with renal syndrome from 1996 to 2005 in Korea. J Bacteriol Virol 2006;36:263–269.
    1. Kim YK, Lee SC, Kim C, Heo ST, Choi C, Kim JM. Clinical and laboratory predictors of oliguric renal failure in haemorrhagic fever with renal syndrome caused by Hantaan virus. J Infect 2007;54:381–386.
    1. Song JW, Kang HJ, Gu SH, Moon SS, Bennett SN, Song KJ, Baek LJ, Kim HC, O'Guinn ML, Chong ST, Klein TA, Yanagihara R. Characterization of Imjin virus, a newly isolated hantavirus from the Ussuri white-toothed shrew (Crocidura lasiura). J Virol 2009;83:6184–6191.
    1. Shin JH, Park BS. Vertebrate fauna, speciation and geological History in the Cheju Island. Korean J Environ Ecol 1998;12:42–57.
    1. Arai S, Gu SH, Baek LJ, Tabara K, Bennett SN, Oh HS, Takada N, Kang HJ, Tanaka-Taya K, Morikawa S, Okabe N, Yanagihara R, Song JW. Divergent ancestral lineages of newfound hantaviruses harbored by phylogenetically related crocidurine shrew species in Korea. Virology 2012;424:99–105.
    1. Kim SH, Jang JY. Correlations between climate change-related infectious diseases and meteorological factors in Korea. J Prev Med Public Health 2010;43:436–444.
    1. National Institute of Meteorological Research. Climate change VI climate: change in Jeju Island. 2010. pp. 1-80.
    1. Kim HJ, Han SW. Diagnostic challenge of hemorrhagic fever with renal syndrome on admission before its serological confirmation. Korean J Nephrol 2004;23:82–91.

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