Infect Chemother. 2008 Sep-Oct;40(5):292-296. Korean.
Published online Oct 25, 2008.
Copyright © 2008 The Korean Society of Infectious Diseases and The Korean Society for Chemotherapy
Case Report

Post-traumatic Infrapatellar Bursitis due to Mycobacterium fortuitum in an Immunocompetent Patient

Dong Won Park, M.D.,1 Ji Eun Kim, M.D.,1 Su Young Back, M.D.,1 Hye Sun Park, M.D.,1 Chang Nam Son, M.D.,1 Seong Eun Ahn, M.D.,1 HyeJeong Park, M.D.,1 Si Hyong Jang, M.D.,2 Seung Sam Paik, M.D.,2 Chung Hyuk Choi, M.D.,3 Tae-Yeal Choi, M.D.,4 and Hyunjoo Pai, M.D.1
    • 1Department of Internal Medicine, Division of Infectious Disease, Hanyang University College of Medicine, Seoul, Korea.
    • 2Department of Histopathology, Hanyang University College of Medicine, Seoul, Korea.
    • 3Department of Orthopedic Surgery, Hanyang University College of Medicine, Seoul, Korea.
    • 4Department of laboratory Medicine, Hanyang University College of Medicine, Seoul, Korea.
Received June 23, 2008; Accepted September 05, 2008.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Mycobacterium fortuitum is a rare pathogen, frequently found in water, soil, animals and plant materials. It can cause infections involving skin, soft tissue and skeletal system after direct inoculation of the pathogen through surgical traumas, punctures and injections. We report a case of infrapatellar bursitis caused by M. fortuitum in an immunocompetent, 42-year-old female, which occurred after bicycle trauma. She experienced marked improvement after surgical excision and debridement of the wound site and antimicrobial therapy.

Keywords
Mycobacterium fortuitum; Rapidly growing mycobacteria; Trauma; Bursitis; Immunocompetent

Figures

Figure 1
Several acid-fast bacilli with long slender brain observed by AFB stain (AFB ×1,000).

Figure 2
PCR-RFLP band patterns by HaeIII (Lanes 1-3) and MspI (Lanes 4-6) digests of PCR-amplified sequences. 2 Bands of Lane M, 25 bp DNA ladder; Lanes 1 and 4, samples from patient; Lanes 2 and 5, M. fortuitum type 1 controls; Lanes 3 and 6, M. fortuitum type 2 controls.

References

    1. Mandell GL, Bennett JE, Dolin R. In: Principles and Practice of Infectious Diseases. 6th. Philadelphia: Churchil Livingstone; 2005. pp. 2909-2916.
    1. Goodhart GL. Mycobacterium fortuitum osteomyelitis following trauma. J Orthop Trauma 1993;7:142–145.
    1. Devi DR, Indumathi VA, Indira S, Babu PR, Sridharan D, Belwadi MR. Injection site abscess due to Mycobacterium fortuitum: a case report. Indian J Med Microbiol 2003;21:133–134.
    1. Coney PM, Thrush S. Cutaneous Mycobacterium fortuitum complicating breast reconstruction. J Plast Reconstr Aesthet Surg 2007;60:1162–1163.
    1. Hawkins C, Qi C, Warren J, Stosor V. Catheter-related bloodstream infections caused by rapidly growing nontuberculous mycobacteria: a case series including rare species. Diagn Microbiol Infect Dis 2008;61:187–191.
    1. Silvestre Salvador JF, Betlloch MI, Alfonso R, Ramón RL, Morell AM, Navas J. Disseminated skin infection due to Mycobacterium fortuitum in an immunocompetent patient. J Eur Acad Dermatol Venereol 1998;11:158–161.
    1. Winthrop KL, Abrams M, Yakrus M, Schwartz I, Ely J, Gillies D, Vugia DJ. An outbreak of mycobacterial furunculosis associated with footbaths at a nail salon. N Engl J Med 2002;346:1366–1371.
    1. Park CK, Choi JH, Kim HO, Park CW, Lee CH. A Case of Cutaneous Infection with Mycobacterium fortuitum. Korean J Dermatol 2007;45:266–270.
    1. Park YM, Kang H, Cho SH, Cho BK, Kim BJ, Kook YH, Park EM. A case of scrofuloderma caused by Mycobacterium fortuitum. Korean J Infect Dis 1999;31:171–175.
    1. Lee JH, Moon DC, Kwon KS, Chung TH. A case of mycobacterium fortuitum infection at the site for antibiotics susceptibility test. Korean J Dermatol 1993;31:769–774.
    1. Lee JH, Cha HG, Moon DC, Kwon KS, Chung TA. Mycobacterium fortuitum infection of acupuncture sites. Ann Dermatol 1994;6:69–73.
    1. Kim BJ, Lee KH, Park BN, Kim SJ, Bai GH, Kook YH. Differentiation of mycobacterial species by PCR-restriction analysis of DNA (342 base pairs) of the RNA polymerase gene (rpoB). J Clin Microbiol 2001;39:2102–2109.
    1. Seo YH, Kim W, Ann JY, Keum DG. Identification of Mycobacterium species by Multiplex PCR-Restriction Fragment Length Polymorphism Assay. J Infect Dis 1999;31:148–152.
    1. Brown-Elliott BA, Wallace RJ Jr. Clinical and taxonomic status of pathogenic nonpigmented or latepigmenting rapidly growing mycobacteria. Clin Microbiol Rev 2002;15:716–746.
    1. Rotman DA, Blauvelt A, Kerdel FA. Widespread primary cutaneous infection with Mycobacterium fortuitum. Int J Dermatol 1993;32:512–514.
    1. Rosenmeier GJ, Keeling JH, Grabski WJ, McCollough ML, Solivan GA. Latent cutaneous Mycobacterium fortuitum infection in a healthy man. J Am Acad Dermatol 1991;25:898–902.
    1. Winthrop KL, Albridge K, South D, Albrecht P, Abrams M, Samuel MC, Leonard W, Wagner J, Vugia DJ. The clinical management and outcome of nail salon-acquired Mycobacterium fortuitum skin infection. Clin Infect Dis 2004;38:38–44.
    1. Olson ES, Simpson AJ, Norton AJ, Das SS. ot everything acid fast is Mycobacterium tuberculosis--a case report. J Clin Pathol 1998;51:535–536.
    1. El Amin NM, Hanson HS, Pettersson B, Petrini B, Von Stedingk LV. Identification of non-tuberculous mycobacteria: 16S rRNA gene sequence analysis vs. conventional methods. Scand J Infect Dis 2000;32:47–50.
    1. Brown-Elliott BA, Wallace RJ Jr, Crist CJ, Mann L, Wilson RW. Comparison of in vitro activities of gatifloxacin and ciprofloxacin against four taxa of rapidly growing mycobacteria. Antimicrob Agents Chemother 2002;46:3283–3285.
    1. Wallace RJ Jr, Bedsole G, Sumter G, Sanders CV, Steele LC, Brown BA, Smith J, Graham DR. Activities of ciprofloxacin and ofloxacin against rapidly growing mycobacteria with demonstration of acquired resistance following single-drug therapy. Antimicrob Agents Chemother 1990;34:65–70.
    1. Wallace RJ Jr, Brown BA, Onyi GO. Susceptibilities of Mycobacterium fortuitum biovar. fortuitum and the two subgroups of Mycobacterium chelonae to imipenem, cefmetazole, cefoxitin, and amoxicillin-clavulanic acid. Antimicrob Agents Chemother 1991;35:773–775.
    1. Wallace RJ Jr, Brown-Elliott BA, Ward SC, Crist CJ, Mann LB, Wilson RW. Activities of linezolid against rapidly growing mycobacteria. Antimicrob Agents Chemother 2001;45:764–767.

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