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HOME > Endocrinol Metab > Volume 25(1); 2010 > Article
Case Report Autoimmune Thyroiditis during Antiviral Therapy with Peginterferon.
Jung Min Roh, Jeong Seon Yoo, Yoon Bum Lee, Hye Rim An, Hong Kyu Choi, Kyo Tae Jung, Jong Suk Park, Kwan Sik Lee, Kyung Rae Kim
Endocrinology and Metabolism 2010;25(1):68-71
DOI: https://doi.org/10.3803/jkes.2010.25.1.68
Published online: March 1, 2010
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Department of Internal Medicine, Yonsei University College of Medicine, Korea.
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Abstract

Combination treatment with pegylated interferon and ribavirin has been established as a standard therapy for chronic hepatitis C. Although interferon therapy is relatively safe, an important side effect is the induction of autoantibodies and autoimmune disease, especially autoimmune thyroid disease. Interferon associated autoimmune thyroid disease can consist of autoimmune hypothyroidism, Graves' disease, and destructive thyroiditis. Thyroid disease may lead to dose reduction or discontinuation of therapy.

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