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Acute toxicity of titanium dioxide nanoparticles on some serum parameters and enzyme activities of Cyprinus carpio

Yıl 2020, Cilt: 5 Sayı: 4, 704 - 710, 31.12.2020

Mustafa Tunçsoy Servet Duran

https://doi.org/10.35229/jaes.818260
Cited By: 1

Öz

Titanium dioxide nanoparticles (TiO2 NPs) are widely used in industries for electronics, packaging, food, and cosmetics. Due to their extensive usage of these NPs pose a great threat to the aquatic environments. Effects of 25 and 50 mg/L waterborne TiO2 NPs on serum glucose, total protein and cholesterol levels and serum AST, ALT and ALP activities of C. carpio were determined after 24, 48 and 96 hours of exposure.
No mortality was observed during the experiments. Serum glucose level increased at 48 and 96 hours while serum total protein and cholesterol levels unchanged compared with control at the end of the 96 hours. There was also an increased in serum AST, ALT and ALP activities compared with control at 96 hours of exposure to TiO2 NPs.

Anahtar Kelimeler

Titanium dioxide Nanoparticle Serum parameters C. carpio

Kaynakça

  • Amelia, M., Lincheneau, C., Silvi, S. & Credi, A. (2012). Electrochemical Properties of CdSe and CdTe Quantum Dots. Chemical Society Review, 41, 5728-5743.
  • Bo, J., Wang, D.J., Li, T.L., Li, Y., Zhang, G., Wang, C. & Zhang, S.Q., (2015). Accumulation and Risk Assessment of Heavy Metals in Water, Sediments and Aquatic Organisms in Rural Rivers in the Taihu Lake Region, China. Environ. Sci. Pollut. Res. 22, 6721-6731.
  • Brown, J.A. (1993). Endocrine Responses to Environmental Pollutants. In: Rankin, J.C., Jensen, F.B. (eds.) Fish Ecophysiology. Chapman and Hall, London, UK, 276–296.
  • Cicik, B. & Engin, K. (2005). The Effects of Cadmium on Levels of Glucose in Serum and Glycogen Reserves in the Liver and Muscle Tissues of Cyprinus carpio (L., 1758). Turk. J. Vet. Anim. Sci., 29, 113-117.
  • Dietschy, J.M., Turley, S.D. & Spady, D.K. (1993). Role of Liver in the Maintenance of Cholesterol and Low Density Lipoprotein Homeostasis in Different Animal Species, Including Humans. J. Lipid Res., 34, 1637-1659.
  • Dutta, H.M. & Haghighi, A.Z. (1986). Methylmercuric Chloride and Serum Cholesterol Levels in Blugill Lepomis macrochirus. Bulletin of Environmental Contamination and Toxicology, 36, 181-185.
  • Federici, G., Shaw, B.J. & Handy, R.D. (2007). Toxicity of Titanium Dioxide Nanoparticles to rainbow trout (Oncorhynchus mykiss): Gill Injury, Oxidative Stress, and Other Physiological Effects. Aquatic Toxicology, 84(4), 415-430.
  • Fırat, Ö. & Kargın, F. (2010). Individual and Combined Effects of Heavy Metals on Serum Biochemistry of Nile Tilapia Oreochromis niloticus. Arch. Environ. Contam. Toxicol., 58, 151-157.
  • Folmar, L.C. (1993). Effects of Chemical Contaminants on Blood Chemistry of Teleost Fish: A Bibliography and Synopsis of Selected Effects. Environ. Toxicol. Chem., 12, 337-375.
  • Hao, L., Wang, Z. & Xing, B. (2009). Effect of Sub-Acute Exposure to TiO2 Nanoparticles on Oxidative Stress and Histopathological Changes in Juvenile Carp (Cyprinus carpio). Journal of Environmental Science, 21, 1459-1466.
  • Hasheesh, W.S., Marie, M.A.S., Abbas, H.H., Eshak, M.G. & Zahran, E.A. (2011). An Evaluation of the Effect of 17α-Methyltestosterone Hormone on Some Biochemical, Molecular and Histological Changes in the Liver of Nile tilapia; Oreochromis niloticus. Life Science Journal, 8(3), 343-358.
  • Heydarnejad, M.S., Khosravian-Hemami, M., Nematollahi, A. & Rahnama, S. (2013). Effects of Copper at Sublethal Concentrations on Growth and Biochemical Parameters in Rainbow Trout (Oncorhynchus mykiss). International Review of Hydrobiology, 98, 71-79.
  • Iwama, G.K., Vijayan, M.M., Forsyth, R.B. & Ackerman, P.A. (1999). Heat Shock Proteins and Physiological in Fish. American Zoologist, 39, 901-909.
  • Javed, M. & Usmani, N. (2015). Impact of Heavy Metal Toxicity on Hematology and Glycogen Status of Fish: A review. Proceedings of the National Academy of Sciences, 85, 889- 900.
  • Ji, C.L., Wang, Q., Wu, H.F., Tan, Q.G. & Wang, W.X. (2015). A Metabolomic Investigation of the Effects of Metal Pollution in Oysters Crassostrea hongkongensis. Mar. Pollut. Bull., 90, 21-222.
  • Jiraungkoorskul, W., Upatham, E.S., Kruatrachue, M., Shaphong, S., Vichasri-Grams, S. & Pokethitiyook, P. (2003). Biochemical and Histopathological Effects of Glyphosate Herbicide on Nile Tilapia (Oreochromis niloticus). Environmental Toxicology, 18, 260-267.
  • Kaviani, F.E., Naeemi, A.S. & Salehzadeh, A. (2018). Acute toxicity and effects of titanium dioxide nanoparticles (TiO2 NPs) on some metabolic enzymes and hematological indices of the endangered Caspian trout juveniles (Salmo trutta caspius Kessler, 1877). Iranian Journal of Fisheries Sciences, 19(3), 1253-1267.
  • Kori-Siakpere, O. & Ubogu, E. (2008). Sublethal Hematological Effects of Zinc on the Freshwater Fish, Heteroclarias sp. (Osteichthyes: Clariidae). African Journal of Biotechnology, 7(12), 2068-2073.
  • Lan, W.G., Wong, M.K., Chen, N. & Sin, Y.M. (1995). Effect of Combined Copper, Zinc, Chromium, and Selenium by Orthogonal Array Design on Alkaline Phosphatase Activity in Liver of the Red Sea Bream, Chrysophrys major. Aquaculture, 131, 219-230.
  • Li, Z.H., Velisek, J., Grabic, R., Li, P., Kolarova, J. & Randak, T. (2011). Use of Hematological and Plasma Biochemical Parameters to Assess the Chronic Effects of a Fungicide Propiconazole on a Freshwater Teleost. Chemosphere, 83, 572-578.
  • Mansouri, B., Maleki, A., Davari, B., Johari, S.A., Shahmoradi, B., Mohammadi, E. & Shahsavari, S. (2016). Histopathological Effects Following Short-Term Coexposure of Cyprinus carpio to Nanoparticles of TiO2 and CuO. Environmental Monitoring and Assessment, 188(575), 5-12.
  • McDonald, M.D. & Grosell, M. (2006). Maintaining Osmotic Balance with an Aglomerular Kidney. Comp. Biochem. Physiol., 143, 447-58.
  • Palma, P., Ledo, L. & Alvarenga, P. (2015). Assessment of Trace Element Pollution and Its Environmental Risk to Freshwater Sediments Influenced by Anthropogenic Contributions: The Case Study of Alqueva Reservoir (Guadiana Basin). Catena, 128, 174-184.
  • Pretto, A., Loro, V.L., Silva, V.M.M., Salbego, J., de Menezes, C.C., Souza, C.F., Gioda, C.R. & Baldisserotto, B. (2014). Exposure to Sublethal Concentrations of Copper Changes Biochemistry Parameters in Silver Catfish, Rhamdia quelen, (Quoy & Gaimard, 1824). Bulletin Environmental Contamination and Toxicology, 392-399.
  • Ramesh, M., Senthil Kumaran, S., Kavith, C., Saravanan, M. & Mustafa, A. (2007). Primary Stress Responses of Common Carp, Cyprinus carpio Exposed to Copper Toxicity. Acta Ichthyologica et Piscatoria, 37, 81-85.
  • Schaperclaus, W., Kulow, H. & Schreckenbach, K. (1992). In: Fish Diseases, vol. 1. Rotterdam, Septicemia of Fish, Fish Disease Leaflet, 68, 1-24.
  • Shaheen, T. & Akhtar, T. (2012). Assessment of Chromium Toxicity in Cyprinus carpio through Hematological and Biochemical Blood Markers. Turkish Journal of Zoology, 36, 682-690.
  • Singh, H.S. & Reddy, T.V. (1990). Effect of Copper Sulfate on Hematology, Blood Chemistry, and Hepato-somatic Index of an Indian Catfish, Heteropneustes fossilis (Bloch), and Its Recovery. Ecotoxicology and Environmental Safety 20, 30-35. Singh, R.K. & Sharma, B. (1998). Carbufuran Induced Biochemical Changes in Clarias batrachus. Pestic. Sci., 53, 285-290.
  • Tang, F., Li, L. & Chen, D. (2012). Mesoporous Silica Nanoparticles: Synthesis, Biocompatibility and Drug Delivery. Advance Materials, 24, 1504-1534.
  • Tunçsoy, M. (2019). Influence of Copper Oxide Nanoparticles on Some Serum Parameters of Clarias gariepinus. Anatolian Env. and Anim. Sciences, 4(3), 387-392.
  • Wang, S.L., Xu, X.R., Sun, Y.X., Liu, J.L. & Li, H.B. (2013). Heavy Metal Pollution in Coastal Areas of South China: A Review. Mar. Pollut. Bull., 76(1-2), 7-15.
  • Wedemeyer, G.A. & Mcleay, D.J. (1981). Metods for Determining the Tolerance of Fishes to Environmental Stressors. In Stress and Fishes. (Edited by Pickering, A.D.), 247-275.
  • Weir, A., Westerhoff, P., Fabricius, L., Hristovski, K. & von Goetz, N. (2012). Titanium dioxide nanoparticles in food and personal care products. Environ Sci Technol, 46(4), 2242-50.
  • Wu, R.S., Pollino, C.A., Au, D.W., Zheng, D.W., Yuen, B. & Lam, P.K. (2003). Evaluation of Biomarkers of Exposure and Effect in Juvenile Areolated Grouper (Epinephelus areolatus) on Food-Borne Exposure to Benzo-a-Pyrene. Environmental Toxicology and Chemistry, 22, 68-73.
  • Yang, J.L. & Chen, H.C. (2003). Effects of Gallium on Common Carp (Cyprinus carpio): Acute Test, Serum Biochemistry, and Erythrocyte Morphology. Chemosphere, 53, 877-882.
  • Zaghloul, K.H., Omar, W.A. & Abo-Hegab, S. (2006). Toxicity Specificity of Copper in Some Freshwater Fishes. Egyptian Journal of Zoology, 47, 383-400.
  • Zikic, R.V., Stajn, S., Pavlovic, Z., Ognjanovic, B.I. & Saicic, Z.S. (2001). Activities of Superoxide Dismutase and Catalase in Erytrocyte and Plasma Transaminases of Goldfish (Carassius auratus gibelio Bloch.) Exposed to Cadmium. Physiol. Res., 50, 105-111.

Titanyum dioksit nanopartiküllerinin Cyprinus carpio’da bazı serum parametreleri ile serum enzim aktiviteleri üzerine akut toksisitesi

Yıl 2020, Cilt: 5 Sayı: 4, 704 - 710, 31.12.2020

Mustafa Tunçsoy Servet Duran

https://doi.org/10.35229/jaes.818260
Cited By: 1

Öz

Titanyum dioksit nanopartikülleri (TiO2 NP) elektronik malzemeler, paketleme, yiyecek endüstrisi ve kozmetik ürünler başta olmak üzere yaygın kullanıma sahip nanopartiküllerdir. Bu yaygın kullanım sonucu doğaya daha yüksek düzeylerde salınmaları, özellikle su organizmaları için tehlike oluşturmaktadır. Bu araştırmada TiO2 NP’nin 25 ve 50 mg/L derişimlerinin 24, 48 ve 96 saatlik sürelerle etkisinde C. carpio’da serum glikoz, total protein ve kolesterol düzeyleri ile serum AST, ALT ve ALP enzim aktivitelerinin belirlenmesi amaçlanmıştır.
Belirlenen süre ve derişimlerde TiO2 NP etkisinde balıklarda mortalite gözlenmemiştir. TiO2 NP etkisinde serum glikoz düzeyi her iki derişimde de 48 ve 96 saatlik etki süresinde kontrole oranla önemli düzeyde artış gösterirken, serum total protein ve kolesterol düzeyinde tüm süre ve derişimlerde kontrole oranla herhangi bir değişiklik gözlenmemiştir. Serum AST, ALT ve ALP enzim aktivitesi ise her iki derişimde de 96 saatlik etki süresinde kontrole oranla önemli düzeyde artış göstermiştir.

Anahtar Kelimeler

Titanyum dioksit Nanopartikül Serum parametreleri C. carpio

Kaynakça

  • Amelia, M., Lincheneau, C., Silvi, S. & Credi, A. (2012). Electrochemical Properties of CdSe and CdTe Quantum Dots. Chemical Society Review, 41, 5728-5743.
  • Bo, J., Wang, D.J., Li, T.L., Li, Y., Zhang, G., Wang, C. & Zhang, S.Q., (2015). Accumulation and Risk Assessment of Heavy Metals in Water, Sediments and Aquatic Organisms in Rural Rivers in the Taihu Lake Region, China. Environ. Sci. Pollut. Res. 22, 6721-6731.
  • Brown, J.A. (1993). Endocrine Responses to Environmental Pollutants. In: Rankin, J.C., Jensen, F.B. (eds.) Fish Ecophysiology. Chapman and Hall, London, UK, 276–296.
  • Cicik, B. & Engin, K. (2005). The Effects of Cadmium on Levels of Glucose in Serum and Glycogen Reserves in the Liver and Muscle Tissues of Cyprinus carpio (L., 1758). Turk. J. Vet. Anim. Sci., 29, 113-117.
  • Dietschy, J.M., Turley, S.D. & Spady, D.K. (1993). Role of Liver in the Maintenance of Cholesterol and Low Density Lipoprotein Homeostasis in Different Animal Species, Including Humans. J. Lipid Res., 34, 1637-1659.
  • Dutta, H.M. & Haghighi, A.Z. (1986). Methylmercuric Chloride and Serum Cholesterol Levels in Blugill Lepomis macrochirus. Bulletin of Environmental Contamination and Toxicology, 36, 181-185.
  • Federici, G., Shaw, B.J. & Handy, R.D. (2007). Toxicity of Titanium Dioxide Nanoparticles to rainbow trout (Oncorhynchus mykiss): Gill Injury, Oxidative Stress, and Other Physiological Effects. Aquatic Toxicology, 84(4), 415-430.
  • Fırat, Ö. & Kargın, F. (2010). Individual and Combined Effects of Heavy Metals on Serum Biochemistry of Nile Tilapia Oreochromis niloticus. Arch. Environ. Contam. Toxicol., 58, 151-157.
  • Folmar, L.C. (1993). Effects of Chemical Contaminants on Blood Chemistry of Teleost Fish: A Bibliography and Synopsis of Selected Effects. Environ. Toxicol. Chem., 12, 337-375.
  • Hao, L., Wang, Z. & Xing, B. (2009). Effect of Sub-Acute Exposure to TiO2 Nanoparticles on Oxidative Stress and Histopathological Changes in Juvenile Carp (Cyprinus carpio). Journal of Environmental Science, 21, 1459-1466.
  • Hasheesh, W.S., Marie, M.A.S., Abbas, H.H., Eshak, M.G. & Zahran, E.A. (2011). An Evaluation of the Effect of 17α-Methyltestosterone Hormone on Some Biochemical, Molecular and Histological Changes in the Liver of Nile tilapia; Oreochromis niloticus. Life Science Journal, 8(3), 343-358.
  • Heydarnejad, M.S., Khosravian-Hemami, M., Nematollahi, A. & Rahnama, S. (2013). Effects of Copper at Sublethal Concentrations on Growth and Biochemical Parameters in Rainbow Trout (Oncorhynchus mykiss). International Review of Hydrobiology, 98, 71-79.
  • Iwama, G.K., Vijayan, M.M., Forsyth, R.B. & Ackerman, P.A. (1999). Heat Shock Proteins and Physiological in Fish. American Zoologist, 39, 901-909.
  • Javed, M. & Usmani, N. (2015). Impact of Heavy Metal Toxicity on Hematology and Glycogen Status of Fish: A review. Proceedings of the National Academy of Sciences, 85, 889- 900.
  • Ji, C.L., Wang, Q., Wu, H.F., Tan, Q.G. & Wang, W.X. (2015). A Metabolomic Investigation of the Effects of Metal Pollution in Oysters Crassostrea hongkongensis. Mar. Pollut. Bull., 90, 21-222.
  • Jiraungkoorskul, W., Upatham, E.S., Kruatrachue, M., Shaphong, S., Vichasri-Grams, S. & Pokethitiyook, P. (2003). Biochemical and Histopathological Effects of Glyphosate Herbicide on Nile Tilapia (Oreochromis niloticus). Environmental Toxicology, 18, 260-267.
  • Kaviani, F.E., Naeemi, A.S. & Salehzadeh, A. (2018). Acute toxicity and effects of titanium dioxide nanoparticles (TiO2 NPs) on some metabolic enzymes and hematological indices of the endangered Caspian trout juveniles (Salmo trutta caspius Kessler, 1877). Iranian Journal of Fisheries Sciences, 19(3), 1253-1267.
  • Kori-Siakpere, O. & Ubogu, E. (2008). Sublethal Hematological Effects of Zinc on the Freshwater Fish, Heteroclarias sp. (Osteichthyes: Clariidae). African Journal of Biotechnology, 7(12), 2068-2073.
  • Lan, W.G., Wong, M.K., Chen, N. & Sin, Y.M. (1995). Effect of Combined Copper, Zinc, Chromium, and Selenium by Orthogonal Array Design on Alkaline Phosphatase Activity in Liver of the Red Sea Bream, Chrysophrys major. Aquaculture, 131, 219-230.
  • Li, Z.H., Velisek, J., Grabic, R., Li, P., Kolarova, J. & Randak, T. (2011). Use of Hematological and Plasma Biochemical Parameters to Assess the Chronic Effects of a Fungicide Propiconazole on a Freshwater Teleost. Chemosphere, 83, 572-578.
  • Mansouri, B., Maleki, A., Davari, B., Johari, S.A., Shahmoradi, B., Mohammadi, E. & Shahsavari, S. (2016). Histopathological Effects Following Short-Term Coexposure of Cyprinus carpio to Nanoparticles of TiO2 and CuO. Environmental Monitoring and Assessment, 188(575), 5-12.
  • McDonald, M.D. & Grosell, M. (2006). Maintaining Osmotic Balance with an Aglomerular Kidney. Comp. Biochem. Physiol., 143, 447-58.
  • Palma, P., Ledo, L. & Alvarenga, P. (2015). Assessment of Trace Element Pollution and Its Environmental Risk to Freshwater Sediments Influenced by Anthropogenic Contributions: The Case Study of Alqueva Reservoir (Guadiana Basin). Catena, 128, 174-184.
  • Pretto, A., Loro, V.L., Silva, V.M.M., Salbego, J., de Menezes, C.C., Souza, C.F., Gioda, C.R. & Baldisserotto, B. (2014). Exposure to Sublethal Concentrations of Copper Changes Biochemistry Parameters in Silver Catfish, Rhamdia quelen, (Quoy & Gaimard, 1824). Bulletin Environmental Contamination and Toxicology, 392-399.
  • Ramesh, M., Senthil Kumaran, S., Kavith, C., Saravanan, M. & Mustafa, A. (2007). Primary Stress Responses of Common Carp, Cyprinus carpio Exposed to Copper Toxicity. Acta Ichthyologica et Piscatoria, 37, 81-85.
  • Schaperclaus, W., Kulow, H. & Schreckenbach, K. (1992). In: Fish Diseases, vol. 1. Rotterdam, Septicemia of Fish, Fish Disease Leaflet, 68, 1-24.
  • Shaheen, T. & Akhtar, T. (2012). Assessment of Chromium Toxicity in Cyprinus carpio through Hematological and Biochemical Blood Markers. Turkish Journal of Zoology, 36, 682-690.
  • Singh, H.S. & Reddy, T.V. (1990). Effect of Copper Sulfate on Hematology, Blood Chemistry, and Hepato-somatic Index of an Indian Catfish, Heteropneustes fossilis (Bloch), and Its Recovery. Ecotoxicology and Environmental Safety 20, 30-35. Singh, R.K. & Sharma, B. (1998). Carbufuran Induced Biochemical Changes in Clarias batrachus. Pestic. Sci., 53, 285-290.
  • Tang, F., Li, L. & Chen, D. (2012). Mesoporous Silica Nanoparticles: Synthesis, Biocompatibility and Drug Delivery. Advance Materials, 24, 1504-1534.
  • Tunçsoy, M. (2019). Influence of Copper Oxide Nanoparticles on Some Serum Parameters of Clarias gariepinus. Anatolian Env. and Anim. Sciences, 4(3), 387-392.
  • Wang, S.L., Xu, X.R., Sun, Y.X., Liu, J.L. & Li, H.B. (2013). Heavy Metal Pollution in Coastal Areas of South China: A Review. Mar. Pollut. Bull., 76(1-2), 7-15.
  • Wedemeyer, G.A. & Mcleay, D.J. (1981). Metods for Determining the Tolerance of Fishes to Environmental Stressors. In Stress and Fishes. (Edited by Pickering, A.D.), 247-275.
  • Weir, A., Westerhoff, P., Fabricius, L., Hristovski, K. & von Goetz, N. (2012). Titanium dioxide nanoparticles in food and personal care products. Environ Sci Technol, 46(4), 2242-50.
  • Wu, R.S., Pollino, C.A., Au, D.W., Zheng, D.W., Yuen, B. & Lam, P.K. (2003). Evaluation of Biomarkers of Exposure and Effect in Juvenile Areolated Grouper (Epinephelus areolatus) on Food-Borne Exposure to Benzo-a-Pyrene. Environmental Toxicology and Chemistry, 22, 68-73.
  • Yang, J.L. & Chen, H.C. (2003). Effects of Gallium on Common Carp (Cyprinus carpio): Acute Test, Serum Biochemistry, and Erythrocyte Morphology. Chemosphere, 53, 877-882.
  • Zaghloul, K.H., Omar, W.A. & Abo-Hegab, S. (2006). Toxicity Specificity of Copper in Some Freshwater Fishes. Egyptian Journal of Zoology, 47, 383-400.
  • Zikic, R.V., Stajn, S., Pavlovic, Z., Ognjanovic, B.I. & Saicic, Z.S. (2001). Activities of Superoxide Dismutase and Catalase in Erytrocyte and Plasma Transaminases of Goldfish (Carassius auratus gibelio Bloch.) Exposed to Cadmium. Physiol. Res., 50, 105-111.
Toplam 37 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Makaleler
Yazarlar

Mustafa Tunçsoy 0000-0001-7306-0539

Servet Duran 0000-0002-1496-1932

Yayımlanma Tarihi 31 Aralık 2020
Gönderilme Tarihi 30 Ekim 2020
Kabul Tarihi 6 Aralık 2020
Yayımlandığı Sayı Yıl 2020 Cilt: 5 Sayı: 4

Kaynak Göster

APA Tunçsoy, M., & Duran, S. (2020). Titanyum dioksit nanopartiküllerinin Cyprinus carpio’da bazı serum parametreleri ile serum enzim aktiviteleri üzerine akut toksisitesi. Journal of Anatolian Environmental and Animal Sciences, 5(4), 704-710. https://doi.org/10.35229/jaes.818260

Cited By

Comparison to Toxic Effects of Copper Oxide Nanoparticles and Copper Sulphate on Some Serum Parameters and Enzyme Activities of Oreochromis niloticus
Journal of Anatolian Environmental and Animal Sciences
https://doi.org/10.35229/jaes.987548
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