Journal Article

FZJ-2024-01719

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Community recommendations on cryoEM data archiving and validation

Kleywegt, G. J. ; Adams, P. D. ; Butcher, S. J. ; Lawson, C. L. ; Rohou, A. ; Rosenthal, P. B. ; Subramaniam, S. ; Topf, M. ; Abbott, S. ; Baldwin, P. R. ; Berrisford, J. M. ; Bricogne, G. ; Choudhary, P. ; Croll, T. I. ; Danev, R. ; Ganesan, S. J. ; Grant, T. ; Gutmanas, A. ; Henderson, R. ; Heymann, J. B. ; Huiskonen, J. T. ; Istrate, A. ; Kato, T. ; Lander, G. C. ; Lok, S.-M. ; Ludtke, S. J. ; Murshudov, G. N. ; Pye, R. ; Pintilie, G. D. ; Richardson, J. S. ; Sachse, C.FZJ* ; Salih, O. ; Scheres, S. H. W. ; Schroeder, G. F.FZJ* ; Sorzano, C. O. S. ; Stagg, S. M. ; Wang, Z. ; Warshamanage, R. ; Westbrook, J. D. ; Winn, M. D. ; Young, J. Y. ; Burley, S. K. ; Hoch, J. C. ; Kurisu, G. ; Morris, K. ; Patwardhan, A. ; Velankar, S.

2024
[Verlag nicht ermittelbar] Chester

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Please use a persistent id in citations: doi:10.1107/S2052252524001246  doi:10.34734/FZJ-2024-01719

Abstract: In January 2020, a workshop was held at EMBL-EBI (Hinxton, UK) to discuss data requirements for the deposition and validation of cryoEM structures, with a focus on single-particle analysis. The meeting was attended by 47 experts in data processing, model building and refinement, validation, and archiving of such structures. This report describes the workshop's motivation and history, the topics discussed, and the resulting consensus recommendations. Some challenges for future methods-development efforts in this area are also highlighted, as is the implementation to date of some of the recommendations.

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Contributing Institute(s):

1. Strukturbiologie (ER-C-3)
2. Strukturbiochemie (IBI-7)

Research Program(s):

1. 5352 - Understanding the Functionality of Soft Matter and Biomolecular Systems (POF4-535) (POF4-535)
2. 5241 - Molecular Information Processing in Cellular Systems (POF4-524) (POF4-524)

Appears in the scientific report 2024

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