A Metabolomics Study of the Effects of Eleutheroside B on Glucose and Lipid Metabolism in a Zebrafish Diabetes Model
Abstract
:1. Introduction
2. Results
2.1. EB Improves Disordered Glucose and Lipid Metabolism in Zebrafish
2.2. EB Increases the Expression of the GLUT4 Protein and Alleviates Diabetes Complicated with Liver Injury
2.3. Differential Metabolite Analysis
2.4. Metabolic Pathway Analysis
3. Discussion
4. Materials and Methods
4.1. Drugs and Materials
4.2. Animals and Experimental Design
4.3. Sample Collection
4.4. Measurement of Biochemical Indexes
4.5. Western Blot
4.6. Histopathological Examination
4.7. Metabolite Extraction
4.8. LC-MS Analysis
4.9. Data Anlaysis
4.10. Statistical Analysis
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Abbreviations
References
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Dong, X.; Chen, Q.; Chi, W.; Qiu, Z.; Qiu, Y. A Metabolomics Study of the Effects of Eleutheroside B on Glucose and Lipid Metabolism in a Zebrafish Diabetes Model. Molecules 2024, 29, 1545. https://doi.org/10.3390/molecules29071545
Dong X, Chen Q, Chi W, Qiu Z, Qiu Y. A Metabolomics Study of the Effects of Eleutheroside B on Glucose and Lipid Metabolism in a Zebrafish Diabetes Model. Molecules. 2024; 29(7):1545. https://doi.org/10.3390/molecules29071545
Chicago/Turabian StyleDong, Xuelian, Qiang Chen, Wenyan Chi, Zhidong Qiu, and Ye Qiu. 2024. "A Metabolomics Study of the Effects of Eleutheroside B on Glucose and Lipid Metabolism in a Zebrafish Diabetes Model" Molecules 29, no. 7: 1545. https://doi.org/10.3390/molecules29071545